Schwasta Tablet (Rosuvastatin Calcium)

Adult dose

The initial dose is 5 mg once daily. If greater reductions in LDL cholesterol are required, the maintenance dose can be adjusted accordingly. The maintenance dose is usually 10 mg once daily, with most patients being managed at this dosage. The maintenance dose should be appropriately adjusted at intervals of 4 weeks or longer, based on LDL cholesterol levels, treatment goals, and patient response, with a maximum daily dose of 20 mg.

Child dose

The typical dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5 mg to 20 mg once daily. The dosage should be adjusted based on the individual patient's treatment goals.

This medication should not be used in certain patients. For example, those who are allergic to this medication, have severely impaired liver function, have muscle disorders, or are taking certain immunosuppressants should not take this medication. Patients with significantly reduced kidney function and women who are pregnant or breastfeeding should also avoid this drug. Because this medication can cause muscle problems, individuals with a history of muscle disorders or those susceptible to muscle toxicity should exercise particular caution. It is also advisable for individuals with genetic issues such as lactose intolerance to avoid this medication. This medication can affect liver function, so individuals with a history of liver disease or those who consume alcohol excessively should undergo regular liver function tests before and during treatment. Patients with hypothyroidism or nephrotic syndrome should treat the underlying condition before taking this medication. If symptoms such as muscle pain or weakness occur, it is crucial to inform a healthcare professional immediately, and the medication should be discontinued if necessary. If muscle enzyme levels rise significantly, therapy should be discontinued and the condition monitored. This medication can increase blood concentration when taken with certain drugs, raising the risk of muscle side effects; thus, it is essential to consult a doctor before combining it with other medications. Additionally, taking it with antacids may reduce its effectiveness, so timing of doses should be adjusted accordingly. Women of childbearing potential should ensure effective contraceptive methods are used, and this medication should not be taken during pregnancy. In cases of overdose, there is no specific antidote, so treatment should be symptomatic and liver function and muscle enzyme checks should be performed. Caution is needed while driving or operating machinery as dizziness may occur. This medication may show higher blood concentrations in Asians, so dosage adjustments may be necessary. In children and adolescents, it should be used cautiously considering its potential impact on growth and development.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, immune-mediated necrotizing myopathy, severe muscle weakness, ocular myasthenia, jaundice, liver failure, acute renal failure, oliguria, thrombocytopenia, dyspnea, interstitial lung disease, severe skin adverse reactions.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• hematuria
• diarrhea

This medication is sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. It should also be safely stored at room temperature, between 1°C and 30°C, avoiding extremes of heat or cold.

Appearance

Pink round film-coated tablet

Package unit

28 T / PTP