Cimetidine Tablet (Cimetidine)

Adult dosage

For cimetidine, either take 400 mg orally twice a day (morning, bedtime) or 800 mg once daily (at bedtime). Additionally, take 300 mg orally four times a day (after meals, at bedtime). 400 mg may be increased to four times a day (after meals, bedtime) (up to a total of 1.6 g). For acute exacerbation of acute gastritis and chronic gastritis, take 200 mg twice a day or 400 mg once a day.

Children's dosage

Administered orally in divided doses of 20 to 40 mg per kg of body weight per day.

This drug should be cut very carefully when using a glass ampoule injection, as glass fragments may mix in. Special caution is needed when used for children or the elderly. Patients with hypersensitivity to this drug or allergic to its constituents, as well as patients taking Dofetilide, should not be administered this drug. The risk of cardiac arrhythmia may increase when used in conjunction with Dofetilide. Patients with reduced kidney or liver function, those with a history of drug allergies, the elderly, children under 19 years of age, and patients undergoing dialysis should use this drug with caution. Additionally, this drug can mask symptoms of gastric cancer, so it should be used only after ensuring the malignancy status. This drug can cause various side effects, such as reduced blood cell counts, liver dysfunction, kidney dysfunction, hypersensitivity reactions, endocrine disorders, gastrointestinal symptoms, neurological disorders, cardiovascular disorders, and skin reactions. If any abnormal symptoms occur, immediate discontinuation of the drug and medical attention is required. The minimum effective dose should be used while monitoring the treatment effect, and if ineffective, other treatment methods should be considered. Extra caution is required for the elderly or those with a history of peptic ulcers, and regular blood tests and liver and kidney function tests should be conducted. This drug may interact with various other medications, so careful dose adjustment and caution are needed when used in combination with anticoagulants, anxiolytics, cardiac medications, antidepressants, diabetes medications, etc. Pregnant women or women who may become pregnant should only use this drug when the therapeutic benefits outweigh the risks, and breastfeeding women should discontinue breastfeeding when this drug is administered. Safety in children has not been sufficiently confirmed, so it should be used cautiously only when necessary. The elderly should use this drug with caution, as the drug may remain in their body longer due to reduced kidney function, requiring dose reduction or increased dosing intervals. In case of overdose, serious symptoms such as respiratory depression may occur, necessitating immediate emergency treatment. When used as an injection, rapid intravenous administration may cause arrhythmias or blood pressure drops, so it should be administered slowly. This drug should be kept out of the reach of children, and care should be taken not to transfer it to another container, as this may adversely affect its quality.

Serious side effects

Leukopenia, granulocytopenia, agranulocytosis, thrombocytopenia, pancytopenia, aplastic anemia, autoimmune hemolytic anemia, jaundice, hepatitis, elevated AST and ALT, perivascular hepatic fibrosis, interstitial seizures, acute renal failure, interstitial nephritis, urinary retention, elevated BUN, shock, anaphylaxis-like reaction, hypersensitivity vasculitis, rash, disturbances of consciousness, seizures, confusional states (anxiety, psychosis, depression, agitation, hallucinations, disorientation)

Mild side effects

• Fatigue
• fever
• general malaise
• urinary difficulties
• muscle pain
• joint pain
• pancreatitis
• hair loss
• gynecomastia
• excessive milk secretion

This drug is sensitive to light, so it should be stored in a container that blocks light. Furthermore, it is important to maintain a storage temperature of 1 to 30 degrees Celsius. This ensures that the drug's efficacy is well maintained and can be used safely.

Appearance

Pale green pentagonal tablet

Package unit

1000 tablets/bottle