Medication info
Dongkwang Cefuroxime Axetil Tablet

Dongkwang Cefuroxime Axetil Tablet

Prescription medicationTabletOral
Ingredient · strength
Cefuroxime Axetil›300.72mg / 1 tablet
Manufacturer / importer
Dongkwang Pharmaceutical Co., Ltd.
Appearance
White to off-white oblong film-coated tablet
Packaging
100 tablets [(10 tablets/PTP)×10]
Approval status
Active

MFDS item code 201403509 · Approved 2014.07.30 · Insurance code 645905650

Summary

Main use
Treatment of respiratory tract infections, genitourinary infections (e.g., gonorrhea), skin infections, and early Lyme disease
Who takes it
Adults · Children
Adult dose
For optimal absorption, take after meals. Adults and children aged 12 years and older: For most infections, administer 250mg twice daily. For severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms, administer 500mg twice daily. For urinary tract infections, administer 250mg twice daily. For uncomplicated gonorrhea, administer a single dose of 1g. For Lyme disease, administer 500mg twice daily for 14 days (10~21 days).
Child dose
Infants and children under 12 years: For most infections, administer 125mg twice daily. However, for otitis media in children aged 2 years and older and for severe infections, administer 250mg twice daily. For Lyme disease, administer 250mg twice daily for 14 days (10~21 days). There is insufficient experience with use in infants under 3 months of age. This medicine is not suitable for young children who cannot swallow tablets.

Ingredients

Manufacturer
Dongkwang Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of respiratory tract infections, genitourinary infections (e.g., gonorrhea), skin infections, and early Lyme disease

  • Otitis media
  • sinusitis
  • tonsillitis
  • pharyngitis
  • acute bronchitis
  • chronic bronchitis
  • pneumonia
  • pyelonephritis
  • cystitis
  • urethritis
  • furunculosis
  • pyoderma
View approved original text

Cefuroxime is a broad-spectrum antibiotic effective against various bacterial infections, and is used for the treatment of upper and lower respiratory tract infections (otitis media, sinusitis, tonsillitis, pharyngitis, bronchitis, pneumonia, etc.), genitourinary infections (pyelonephritis, cystitis, urethritis, etc.), and skin and soft tissue infections (furunculosis, pyoderma, impetigo, etc.). It is also effective for the treatment of gonorrhea and early Lyme disease. This medication is stable against beta-lactamase and shows strong bactericidal activity against resistant strains. Cefuroxime is effective against a variety of strains including aerobic and anaerobic Gram-positive and Gram-negative bacteria, making it a reliable option for treating various infections. When used appropriately, it can improve infections and aid in recovery.

How to take

Adult dose

For optimal absorption, take after meals. Adults and children aged 12 years and older: For most infections, administer 250mg twice daily. For severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms, administer 500mg twice daily. For urinary tract infections, administer 250mg twice daily. For uncomplicated gonorrhea, administer a single dose of 1g. For Lyme disease, administer 500mg twice daily for 14 days (10~21 days).

Child dose

Infants and children under 12 years: For most infections, administer 125mg twice daily. However, for otitis media in children aged 2 years and older and for severe infections, administer 250mg twice daily. For Lyme disease, administer 250mg twice daily for 14 days (10~21 days). There is insufficient experience with use in infants under 3 months of age. This medicine is not suitable for young children who cannot swallow tablets.

Precautions

This medication is a cephalosporin antibiotic and should not be used in patients with an allergy to this class of drugs. Patients with a history of allergy to penicillin or other beta-lactam antibiotics, patients with allergic tendencies, patients with severe renal impairment, patients who have difficulty swallowing or elderly patients, and patients in poor general condition should be administered this drug with caution. Most side effects of this drug are mild and temporary, but serious allergic reactions or skin adverse reactions may rarely occur, necessitating vigilance. Commonly observed symptoms may include headaches, dizziness, digestive disturbances, diarrhea, nausea, etc., and in severe cases, pseudomembranous colitis or hepatic dysfunction may occur. Due to potential effects on kidney function, regular testing is needed, and medication should be discontinued immediately if any unusual symptoms occur, and appropriate measures should be taken. When using this drug, it is important to conduct susceptibility tests to prevent the development of antibiotic resistance and to administer it only for the minimum necessary duration. Prior to administration, thorough questioning is necessary to predict allergic reactions or hypersensitivity, and administration should be stopped immediately upon occurrence of any unusual symptoms. Caution should be exercised as prolonged use may lead to excessive growth of Candida or other resistant bacteria. Take care when driving or operating machinery as symptoms such as dizziness may occur. Women who are pregnant or breastfeeding should only use this medication if the benefits outweigh the risks, as its safety during pregnancy and lactation has not been established. Caution should be taken while breastfeeding. Safety in infants under 3 months has not been confirmed, and syrup formulations are preferable for children instead of tablets. Elderly patients have a higher risk of side effects due to diminished bodily function, so dosage and intervals should be adjusted and closely monitored. This drug may affect the results of certain clinical tests, so it is important to inform the healthcare provider during testing. In case of an overdose, seizures may occur due to CNS stimulation, and blood dialysis or peritoneal dialysis can reduce the drug concentration. Finally, keep this medicine out of the reach of children and store it in its original container to prevent misuse and deterioration of quality.

Side effects

  • Candida overgrowth
  • eosinophilia
  • positive Coombs test
  • thrombocytopenia
  • leukopenia
  • granulocytopenia
  • erythropenia
  • decreased hemoglobin
  • decreased hematocrit
  • hemolytic anemia
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  • skin rash
  • urticaria
  • itching
  • drug fever
  • serum sickness
  • anaphylaxis
  • facial edema
  • lymphadenopathy
  • arthralgia
  • headache
  • dizziness
  • diarrhea
  • nausea
  • abdominal pain
  • vomiting
  • dyspepsia
  • constipation
  • loss of appetite
  • pseudomembranous colitis
  • abdominal distension
  • fever
  • cough
  • dyspnea
  • abnormal chest X-ray
  • temporary increase in liver enzymes
  • jaundice
  • hepatitis
  • increased BUN
  • acute renal failure
  • erythema multiforme
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • symptoms of vitamin K deficiency
  • symptoms of vitamin B complex deficiency
  • ear pain
  • perioral sensory disturbances
  • tingling of the tongue
  • pharyngeal abnormalities
  • dry mouth
  • palpitations
  • eczema
  • DRESS syndrome
  • shock symptoms
  • malaise
  • oral abnormalities
  • wheezing
  • dizziness
  • bowel movements
  • tinnitus
  • sweating
  • Conn's syndrome

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air exposure and kept in a cool place below 30 degrees Celsius. Proper storage will help maintain the drug's efficacy over time.

Appearance and packaging

Appearance

White to off-white oblong film-coated tablet

Package unit

100 tablets [(10 tablets/PTP)×10]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.