Clarithromycin Tablet 250mg (Clarithromycin)

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) per dose twice daily; for severe infections, administer 500mg (potency) per dose twice daily. The usual duration of treatment is 7～14 days. For patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children 12 years of age and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in patients who are allergic to specific ingredients or have had hypersensitivity reactions to certain antibiotics. Additionally, patients with cardiac rhythm disturbances, severe liver dysfunction, or significant kidney impairment must consult a physician before using this medication. It is generally safer for pregnant or nursing women to avoid taking this drug. During the course of taking this medication, it is possible to experience rare allergic reactions or severe skin reactions, so if symptoms such as rash, itching, or difficulty breathing occur, immediate medical attention should be sought. Gastrointestinal side effects may include abdominal pain, diarrhea, and nausea. If severe diarrhea or abdominal pain persists, the medication should be discontinued and a doctor consulted. This drug may affect liver and kidney function, so patients with liver or kidney diseases should have regular tests to monitor their condition. Furthermore, this medication can interact with various other medications, so if other drugs are being taken, it should be communicated to the healthcare provider, especially if heart-related drugs, certain antibiotics, anticoagulants, or antidiabetic drugs are being used. Elderly patients may have decreased physical function, so caution is particularly needed when using this drug. Prolonged or repeated use of the medication can lead to the emergence of resistant bacteria, so it should be taken for the minimum duration as directed by a physician. Finally, this medication can cause dizziness or confusion during driving or operating machinery, so be cautious.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste alterations, loss of appetite, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute exacerbation of maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremor, paresthesia, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, tinnitus, auditory impairment, hypoglycemia, purpuric rash, phlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urinary discoloration

This medicine should be stored at room temperature between 1 and 30 degrees Celsius, preferably in a container that protects it from light and allows for good air circulation. Proper storage helps maintain the drug's effectiveness and prevents degradation.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle