Ceftron Injection 1.0 Gram (Ceftriaxone Sodium Hydrate)

Adult administration

For adults and children over 12 years, administer 1-2g (potency) of ceftriaxone once daily via intravenous or intramuscular injection. In cases of severe infections or infections caused by moderately susceptible pathogens, the dosage may be increased up to 4g (potency) once daily. Elderly patients should follow the same adult dosage and administration without any modification. For gonorrhea treatment, a single intramuscular dose of 250mg (potency) is recommended. For infection prevention before and after surgery

Child administration

For neonates (within 14 days of birth), administer 20-50mg (potency) per Kg of body weight once daily, not to exceed 50mg (potency). For infants and children (15 days to 12 years), administer 20

This drug should not be mixed or administered simultaneously with calcium-containing solutions. Particularly in newborns, if administered with calcium, precipitate formation can occur, leading to serious issues and must not be used. Patients who have an allergy to this drug or have had hypersensitivity reactions to cephalosporins or penicillins should not use it. Additionally, it should not be used in premature infants, infants with jaundice, or those with issues in binding bilirubin. Those with a history of drug allergies or allergic conditions like asthma should use this medication cautiously, and dosage adjustments may be necessary for patients with poor kidney function. Elderly patients or those in poor general condition should have regular blood tests to prevent symptoms of vitamin K deficiency. This drug can cause various side effects, including injection site pain, rash, diarrhea, and increased liver enzymes. Rarely, severe allergic reactions, encephalopathy, or acute renal failure may occur, so any abnormal symptoms should be reported to healthcare professionals immediately. During administration, it is important to regularly perform liver, kidney, and blood tests to check for abnormalities. Additionally, this drug may cause dizziness or other symptoms that necessitate caution when driving or operating machinery. Caution should be exercised when using it in conjunction with other drugs, especially with diuretics, aminoglycoside antibiotics, and vitamin K antagonists, as they may increase the risk of renal impairment or bleeding. Pregnant or breastfeeding women should consult a doctor before using this drug, as it may affect the fetus or newborn. The safety of this drug in newborns and premature infants has not been established, and special precautions should be taken due to the risk of bilirubin encephalopathy. In the case of overdose, there is no specific antidote, and appropriate treatment according to symptoms should be provided. During the administration of this drug, it should only be used for the necessary duration to prevent infections and the development of resistant bacteria.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction, high fever accompanied by severe rash, blisters, skin peeling, pain of oral/ocular mucosa, severe skin reaction, asthma attack, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, liver abnormalities (jaundice), sudden and very severe headache, thunderclap headache

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• dizziness
• bronchospasm
• loose stools
• nausea

This drug should be stored in a sealed container to prevent air or moisture from entering, preferably at room temperature between 1°C and 30°C. This storage condition helps to preserve the drug's effectiveness for a longer period.

Appearance

White to pale yellow crystalline powder filled in a colorless transparent vial

Package unit

10 vials