Ceftron Injection 0.5 grams (Ceftriaxone Sodium Hydrate)

Adult administration

Adults and children over 12 years should receive 1-2g (based on potency) of ceftriaxone intravenously or intramuscularly once daily. For infections caused by pathogens showing moderate or severe susceptibility, the dose may be increased up to 4g (based on potency) once daily. For gonorrhea treatment, a single intramuscular injection of 250mg (based on potency) is recommended. For the prevention of infections before and after surgery, 1-2g (based on potency) should be administered once, 30-90 minutes prior to surgery, depending on the risk of infection.

Child administration

In infants (within 14 days of birth), administer 20-50mg (based on potency) per kg of body weight once daily, not exceeding 50mg (based on potency) per kg. Children and infants (from 15 days to 12 years) should be dosed based on body weight.

This medication should not be mixed or administered simultaneously with solutions or drugs containing calcium. Especially in neonates, the combination of this drug and calcium can produce precipitates, and it should not be administered. Patients with allergies to this drug or a history of hypersensitivity to cephalosporins or penicillin antibiotics should not use it. If it contains lidocaine, intravenous administration is prohibited. Caution is advised when administering to patients with impaired kidney function, a history of drug allergies, or those with allergic tendencies such as bronchial asthma. Elderly patients or those in poor general condition also require careful monitoring. While using this drug, it is important to perform regular blood, liver, and kidney function tests to detect adverse reactions early. Rarely, skin rash, diarrhea, headache, dizziness, and blood abnormalities may occur, and any symptoms should be reported to healthcare professionals immediately. In case of overdose, which cannot be removed by hemodialysis or peritoneal dialysis, immediate symptomatic treatment is necessary. Pregnant or nursing women should consult with a specialist before using this drug, as it may affect the fetus or newborn. This drug may cause side effects such as dizziness when driving or operating machinery, hence caution is advised. When using this drug in conjunction with other medications, interactions should be monitored closely, especially with diuretics, aminoglycoside antibiotics, and vitamin K antagonists, as the risk of renal impairment or bleeding may increase, requiring guidance from a specialist. Finally, it is advisable to use the prepared solution as soon as possible, with a recommendation to use it within 6 hours at room temperature or within 24 hours if refrigerated.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary symptoms.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• itching
• hematuria
• diabetes
• phlebitis

This medication should be stored in a sealed container to prevent exposure to air or moisture, preferably at room temperature between 1 to 30 degrees Celsius. This storage helps maintain the drug's efficacy and prevents degradation.

Appearance

A colorless transparent vial filled with white to light yellow crystalline powder.

Package unit

10 vials