Clarithromycin Tablet 250mg

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years or older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This drug should not be used by patients with certain medications or diseases. For example, it should not be administered to individuals with an allergy to this medication or those with severely impaired heart, liver, or kidney function. Pregnant or nursing women should also avoid taking this medication. When administering this drug, caution should be exercised with patients who have poor liver or kidney function, older patients, and those with heart diseases. Care should also be taken regarding drug interactions when given in conjunction with other antibiotics. This medication can rarely cause various side effects including allergic reactions, skin rashes, digestive disturbances, liver function abnormalities, kidney issues, central nervous system symptoms, etc. Therefore, if any unusual symptoms appear during administration, it is important to consult a doctor immediately. There is a high possibility of this drug interacting with other medications. Extra caution is advised when taken with drugs that affect the heart or are metabolized in the liver. Before taking the medication, it is essential to inform medical personnel of any current medications being taken. Pregnant or nursing women should not take this medication. If it must be taken, breastfeeding should be discontinued. In the case of children, the safety and efficacy of this drug have not been adequately studied; therefore, it is generally not recommended for use in children under 12 years of age. Elderly patients may require dosage adjustment due to increased drug concentration as a result of reduced kidney function. Overdosing this medication can result in gastrointestinal disturbances or psychiatric symptoms. In case of overdose, appropriate medical treatment should be sought immediately. This medication should not be refrigerated during storage; it should be kept away from direct sunlight and stored at room temperature. Lastly, during the course of taking this medication, it is important to be cautious with driving or operating machinery as dizziness or confusion may occur.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal ulceration, epigastric pain, thirst, tooth discoloration, pancreatitis, increased amylase, dysgeusia, loss of appetite, constipation, discoloration of stools, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, paresthesia, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug eruption associated with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, gustatory dysfunction, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, auditory impairment, purpuric rash, acute generalized pustular psoriasis, muscle cramps, musculoskeletal rigidity, myopathy, elevated serum creatinine, elevated serum urea, nephritis, phlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. The storage temperature should be kept at room temperature between 1 and 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet with vanilla flavor

Package unit

30 tablets/bottle, 200 tablets/bottle