Ceftriaxone Sodium Hydrate Injection 2g

Adult administration

For adults and children over 12 years: administer 1–2g (as ceftriaxone) intravenously or intramuscularly once daily. In cases of severe infection or infections caused by moderately sensitive pathogens, the dosage can be increased up to 4g (as ceftriaxone) once daily. Elderly patients should follow the adult dosage without modification. For gonorrhea treatment, a single intramuscular injection of 250mg (as ceftriaxone) is recommended. For the prevention of postoperative infections:

Child administration

For neonates (up to 14 days old): 20–50mg per Kg of body weight administered once daily, not exceeding 50mg. For infants and children (15 days to 12 years): 20–

This medication should not be mixed or administered simultaneously with calcium-containing solutions. In particular, it should never be used with calcium solutions in neonates under 28 days old as it may pose risks. This drug can react with calcium and form precipitates, which can cause life-threatening problems in the lungs or kidneys of neonates and premature infants. Therefore, when administering this drug, a different injection site from the calcium-containing solution should be used, and the time of administration should be separated. Patients with a history of allergy to this drug or hypersensitivity to cephalosporins or penicillins should not use this medication. Additionally, this drug contains lidocaine and should not be administered intravenously; premature infants and neonates with bilirubin binding issues should not use this medication. Patients with severe kidney disease or a history of drug allergies should use this medication cautiously and may require dosage adjustments or changes in the dosing interval. This medication can cause side effects such as leukopenia, thrombocytopenia, elevated liver enzymes, diarrhea, and rashes, so regular monitoring is necessary during administration. If severe allergic reactions or shock symptoms appear, administration should be stopped immediately, and appropriate treatment should be administered. Like other antibiotics, this medication may alter the normal intestinal flora and cause severe diarrhea or colitis, so caution is advised if symptoms occur. Pregnant or nursing women should consult their physician as the use of this medication may affect the fetus or infant. Older adults may have reduced bodily functions and a higher risk of side effects, so dosage and intervals should be carefully monitored. Regular testing for blood, liver, and kidney function, as well as bleeding risks, is essential during the administration of this drug. Finally, this medication should be used as soon as possible after preparation, and when stored, it should be used within 6 hours at room temperature and within 24 hours under refrigeration.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, high fever with severe rash, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, difficulty or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, liver abnormalities (jaundice), and sudden severe headaches.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• elevated liver enzymes
• headache
• dizziness
• bronchospasm
• nausea

This medication should be stored in a sealed container to prevent exposure to air, maintaining a storage temperature between 1 and 30 degrees Celsius. Proper storage ensures prolonged stability of the drug.

Appearance

A white to pale yellow crystalline powder filled in a colorless and transparent vial

Package unit

1 vial × 10 pieces