Crossta Tablet 5 mg (Rosuvastatin Calcium)

Adult dose

The initial dosage is 5 mg once daily, and if more LDL-cholesterol reduction is needed, it can be adjusted to a maintenance dose. The maintenance dose, which is 10 mg once daily, is sufficient for most patients. The maintenance dose should be adjusted appropriately after an interval of 4 weeks or more based on LDL-cholesterol levels, treatment goals, and the patient's response, with a maximum of 20 mg per day.

Child dose

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5 mg to 20 mg once daily. The dosage can be adjusted according to the individual patient's treatment goals.

This medication should not be used in certain patients. For example, patients with an allergy to any ingredient of this medication, those with severe liver dysfunction, patients with muscle diseases, severely impaired renal function, pregnant or breastfeeding women, and women of childbearing age who do not use adequate contraception should not take this medication. Additionally, patients at risk for myopathy or rhabdomyolysis should avoid high doses. Caution is also necessary for those with a history of hypothyroidism or genetic muscle disorders. Patients with genetic issues like lactose intolerance should not take this medication. This medication can affect liver function, so patients who consume a lot of alcohol or have a history of liver disease should undergo regular liver function tests both before and during treatment. If symptoms like muscle pain or weakness occur, they should inform their doctor immediately, and the medication can be stopped if necessary. This medication may interact with other drugs, so caution is needed when taken alongside medications that may increase muscle toxicity. Some medications can increase this medication's blood levels, raising the risk of side effects, so consultation with a doctor is needed during concomitant therapy. Pregnant or breastfeeding women should not use this medication, and women with potential for pregnancy should use adequate contraception while taking this medication, as it may pose potential risks to the fetus and infant. There is no specific antidote for overdose, so treatment should be symptomatic and liver function and muscle enzyme levels should be monitored. Dizziness or muscle-related symptoms may occur during treatment, so caution is needed when driving or operating machinery. Possible side effects of this medication include headaches, dizziness, muscle pain, dyspepsia, and skin rashes, and in rare cases, severe liver damage or muscle destruction may occur. Therefore, regular check-ups and symptom observation are necessary while taking this medication under the doctor's guidance, and healthcare professionals should be consulted immediately if abnormal symptoms occur.

Serious side effects

Hypersensitivity reactions including urticaria, angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), liver abnormalities (jaundice), severe muscle weakness, rhabdomyolysis, dyspnea, respiratory distress and cough, multiple neuropathy, severe skin adverse reactions, acute renal failure, oliguria, chest tightness, difficulty breathing, severe allergic reactions, severe edema or urination abnormalities, severe neurological symptoms

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• hematuria
• diarrhea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to store it at room temperature between 1 degree and 30 degrees Celsius.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle