Crostap 20mg (Rosuvastatin Calcium)

Adult dose

This medication can be administered at any time of the day, regardless of meals. The initial dose is 5mg once daily, and if greater LDL cholesterol reduction is needed, the maintenance dose can be adjusted. The maintenance dose is usually 10mg once daily, and most patients are adjusted at this dose. The dose should be adjusted every 4 weeks or more, based on LDL cholesterol levels, therapeutic goals, and the patient's response, with a maximum daily dose of 20mg.

Child dose

For children aged 10 to 17 years with heterozygous familial hypercholesterolemia, the dosage is administered once daily in the range of 5mg to 20mg, adjusting the administered dose according to the individual therapeutic goals.

This medicine should not be used in certain patients. For instance, anyone with an allergy to the ingredients of this medicine, those with active liver disease, muscle disorders, severe kidney dysfunction, pregnant or breastfeeding women, and women of childbearing age who do not use appropriate contraception should not take this medicine. Additionally, individuals at higher risk of muscle disorders should avoid high doses, and those with a history of hypothyroidism or genetic muscle disorders should exercise caution. This medicine contains lactose, so individuals with lactose intolerance or related genetic disorders should not take it. Those with liver or kidney problems or those who consume large amounts of alcohol should consult a physician before starting this medicine and should have regular liver function tests during treatment. If side effects such as muscle pain or weakness occur, notify medical personnel immediately, and the medication may be discontinued if necessary. This medicine may interact with other medications, so you must inform your doctor if you are taking any other drugs. In particular, the use of this drug in conjunction with certain antiviral medications, immunosuppressants, antifungals, some antibiotics, and fibrate-class drugs may increase the risk of muscle disorders. Women who are pregnant or planning to become pregnant should not take this medication, and if pregnancy occurs, the medication should be discontinued immediately. The use of this medicine during breastfeeding is also not recommended. In case of overdose, there is no specific antidote, so symptomatic treatment should be sought immediately, and liver function and muscle enzyme levels should be monitored. Finally, this medication can rarely cause serious skin reactions, liver damage, and neurological side effects, so if symptoms such as skin rash, jaundice, severe muscle pain, or memory loss occur, consult a physician immediately.

Serious side effects

Allergic reactions including urticaria and angioedema, pancreatitis, myopathy, rhabdomyolysis, severe muscle weakness, oculomotor palsy, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, jaundice, hepatitis, acute renal failure, oliguria, thrombocytopenia, increased serum creatinine, interstitial lung disease, fatal and non-fatal liver failure, severe allergic reactions

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• hematuria
• diarrhea

This medication may be sensitive to air or moisture, so it must be stored in a sealed container. It is best to maintain the storage temperature between 1 to 30 degrees Celsius at room temperature. Proper storage can help maintain the effectiveness of the medicine.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP×3)]