Kvastin Tablets 10mg (Rosuvastatin Calcium)

Adult dose

Regardless of meals, administer 5mg once daily at any time of the day. If a greater reduction in LDL cholesterol is required, the maintenance dose can be adjusted to 10mg once daily. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response over a period of 4 weeks or more, with a maximum daily dose of 20mg.

Child dose

For children aged 10 to 17 years with heterozygous familial hypercholesterolemia, the dosage ranges from 5mg to 20mg once daily. The dosage should be adjusted based on the individual patient's treatment goals over a period of 4 weeks or more.

This medication should not be used in certain patients. For instance, it should not be administered to those allergic to its ingredients, patients with active liver disease, those with muscle disorders, patients with severe renal impairment, or pregnant or breastfeeding women. Additionally, high-dose administration is prohibited in patients at risk for muscle disorders. This medication contains lactose and is not recommended for patients with lactose intolerance. Liver function and muscle condition should be monitored regularly during administration. Patients who consume large amounts of alcohol or have a history of liver disease need to be particularly cautious. If symptoms of muscle pain or weakness occur, inform a physician immediately, and medication may need to be discontinued if necessary. This medication can interact with various drugs, so it is crucial to consult a physician or pharmacist if you are taking other medications. Special caution is required when combined with certain antiviral drugs, immunosuppressants, antifungals, and antibiotics. Women who may become pregnant should practice adequate contraception during treatment with this medication, and if pregnancy is confirmed, the use of this medication should be discontinued immediately. Breastfeeding women should also refrain from using this medication for safety. In cases of overdose, there is no specific antidote; therefore, symptomatic treatment and monitoring of liver function and muscle enzyme levels are necessary. Rarely, side effects such as headaches, dizziness, dyspepsia, rashes, muscle pain, weakness, hematuria, diarrhea, chest discomfort, loss of appetite, abdominal bloating, abnormal liver function tests, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, fatigue, numbness, and sensory disturbances may occur, and consultation with a physician is advised if symptoms arise. Caution is advised when driving or operating machinery as dizziness may occur. Lastly, this medication may accumulate more in Asian individuals, necessitating dosage adjustments.

Serious side effects

Hypersensitivity reactions including urticaria, angioedema, severe edema, chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, exfoliative dermatitis, mucosal pain in the mouth/eyes, Stevens-Johnson syndrome, eosinophilia and systemic symptoms associated with drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, serious liver damage, acute renal failure, oliguria, thrombocytopenia, severe muscle weakness, ocular myopathy

Mild side effects

• Headaches
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• hematuria
• rashes

This medication should be stored in a tightly closed container to prevent exposure to air and moisture and should ideally be kept at room temperature, between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

Pink round film-coated tablet

Package unit

100 tablets/bottle, 30 tablets/bottle