Cregojeong 20 mg (Rosuvastatin Calcium)

Adult dose

Independently of meals, take 5 mg once daily as the initial dose. If a greater reduction in LDL cholesterol is needed, adjust to maintenance doses, which are generally calibrated at 10 mg once daily. Maintenance doses should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, and can be increased to a maximum of 20 mg per day.

Child dose

For pediatric patients aged 10 to 17 years, the dosage is 5 mg to 20 mg once daily. The dosage should be adjusted according to individual treatment goals, with adjustments made after 4 weeks or more.

This medication should not be used in certain patients. For instance, patients who have an allergy to any component of this drug or have severely impaired liver function should avoid its use. Additionally, patients with muscle disorders, severe kidney disease, or those who are pregnant or breastfeeding should not use this medication. Women of childbearing potential should use adequate contraception to minimize the possibility of pregnancy and can only use it when fully aware of the risks to the fetus. This drug has the potential to cause muscle damage, thus, caution is needed in patients with moderate to severe impaired kidney function, hypothyroidism, personal history of genetic muscle disorders, alcoholics, individuals of certain races (Asian descent), and when combined with other specific medications. It contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. It is important to regularly monitor liver function and muscle condition during treatment. If symptoms such as muscle pain, weakness, fatigue, or fever occur, medical personnel should be notified immediately. Also, this medication can interact with several other drugs, so if currently taking any other medication, it is essential to notify the healthcare provider, especially when combining with specific antivirals, immunosuppressants, and fibrate medications. Pregnant or breastfeeding women should not use this medication, and women who may become pregnant must use appropriate contraception. In the case of overdose, no specific antidote exists, and treatment should be symptomatic along with liver and muscle function tests. The effects of this drug on driving or operating machinery are unclear, but caution is required as dizziness may occur. Finally, this medication may rarely produce serious side effects such as severe skin reactions, liver dysfunction, or muscle damage, so if symptoms arise, discontinue use immediately and consult medical personnel.

Serious side effects

Allergic reactions including urticaria and angioedema, liver dysfunction (jaundice), rhabdomyolysis, severe muscle weakness, ocular muscle weakness, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), acute renal failure, oliguria, thrombocytopenia, fatal and non-fatal liver failure, cough and dyspnea (respiratory issues), severe skin adverse reactions, immune-mediated necrotizing myopathy.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1°C and 30°C. This will help maintain the medication's efficacy and safety over time.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle