Colostatin 5 mg (Rosuvastatin Calcium)

Adult dose

This drug can be administered at any time of the day regardless of meals. The initial dose is 5 mg once daily and may be adjusted to a maintenance dose if a greater reduction in LDL cholesterol is needed. The maintenance dose is 10 mg once daily, and most patients are managed at this dosage. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, therapeutic goals, and patient response at intervals of 4 weeks or more.

Child dose

The usual dosage range is 5 mg to 20 mg once daily. The dosage should be individually adjusted according to the recommended therapeutic goals for each patient. The dosage may be adjusted at intervals of 4 weeks or more.

This medication should not be administered to certain patients. For example, individuals allergic to the ingredients of this drug, those with severely impaired liver function, individuals with muscle disorders, and those taking certain medications may be at risk if they take this drug. Pregnant or breastfeeding women, as well as women who may become pregnant, must consult a doctor before taking this medication and should only take it when there is a high certainty that they will not become pregnant. Additionally, this medication contains lactose, and individuals with lactose intolerance should not take it. While taking this medication, liver function and muscle condition should be regularly monitored, especially in those who drink a lot of alcohol or have a history of liver disease. If symptoms like muscle pain, muscle weakness, fatigue, or fever occur, the patient should immediately inform their doctor, and in severe cases, discontinuation of the drug may be necessary. This drug may increase blood concentration when taken with certain medications, heightening the risk of side effects, so it is essential to inform the doctor or pharmacist if taking other medications. Pregnant or breastfeeding women should not take this drug, and women planning to become pregnant should use appropriate contraception. In cases of overdose, there is no specific antidote, so one must visit a medical institution immediately for appropriate treatment. Caution is needed when driving or operating machinery, as dizziness may occur. Finally, this drug may show higher blood concentrations in Asians, which may necessitate dosage adjustments.

Serious side effects

Hives, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, severe muscle weakness, ocular muscle weakness, jaundice, hepatitis, acute renal failure, oliguria, thrombocytopenia, elevated serum creatinine levels, severe allergic reactions, severe skin reactions, shortness of breath, liver dysfunction (jaundice), severe swelling or urination abnormalities

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It should be kept at a temperature between 1 to 30 degrees Celsius, in a location that is not too hot or cold.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle