Crechek Tablet 10 mg (Rosuvastatin Calcium)

Adult dose

This drug can be administered at any time of the day regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose is 10 mg once daily. The maintenance dose should be adjusted based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, with an increase up to a maximum of 20 mg per day.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), the dosage ranges from 5 mg to 20 mg once daily, and the dosage should be adjusted individually with an interval of 4 weeks or more.

This drug should not be administered to certain patients. For example, it should not be used in patients with an allergy to the components of this drug, severely impaired liver function, muscle disease, severely reduced kidney function, women who are pregnant or breastfeeding, and in cases where it is taken with certain medications. It is important to regularly check liver function and muscle condition while using this drug. Patients who consume large amounts of alcohol, have a history of liver disease, hypothyroidism, decreased kidney function, and elderly patients should be especially cautious. If symptoms such as muscle pain, weakness, or cramps occur, notify healthcare personnel immediately, and it may be necessary to discontinue the medication. It is advisable to avoid conducting muscle-related tests immediately after intense exercise. This drug can affect liver function; therefore, treatment should be stopped immediately if jaundice or symptoms of liver damage appear. Blood sugar levels should also be monitored regularly, as the risk of diabetes may increase. The effectiveness and side effects of this drug may vary according to certain genetic factors, necessitating dosage adjustments based on the patient's condition. Severe skin reactions can occur rarely, so if severe rashes, redness, or swelling occur on the skin, the medication should be stopped immediately and medical advice sought. Concomitant use with other drugs may lead to interactions, so it is essential to inform healthcare personnel about all medications being taken. Notably, using this drug with specific antivirals, immunosuppressants, antibiotics, and fibrate medications may increase the risk of muscle-related side effects. Women who are pregnant or potentially pregnant must use adequate contraceptive methods, and should discontinue use immediately if pregnancy occurs. Use while breastfeeding is also not recommended. In cases of overdose, there are no specific antidotes, so treatment should be symptomatic while managing liver and muscle examinations. Dizziness may occur while taking this drug, so caution is advised when driving or operating machinery.

Serious side effects

Hypersensitivity reactions including urticaria and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms, rhabdomyolysis, severe muscle weakness, ocular muscle weakness, jaundice, hepatitis, acute renal failure, oliguria, severe edema, chest tightness, dyspnea, severe skin reactions, severe allergic reactions, severe edema or urination abnormalities, difficulty breathing, severe rash with fever, blisters,

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• diarrhea
• rash

This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is best to store the drug at room temperature between 1°C and 30°C, away from extreme heat or cold.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2), 30 tablets/bottle