Soktin Tablets (Cimetidine)

Adult dosage

For cimetidine, administer 400 mg orally, twice daily (morning and bedtime) or once daily at bedtime at 800 mg. Also, administer 300 mg orally, four times daily (after meals and at bedtime). The dose can be increased to 400 mg, four times daily (after meals and at bedtime) (total 1.6 g). For the improvement of gastric mucosal lesions during acute gastritis and acute exacerbations of chronic gastritis, administer 200 mg orally, twice daily or once daily at 400 mg.

Children's dosage

Administer 20 to 40 mg per kg of body weight daily, divided into oral doses.

This medication should be handled with care when cutting the container, as glass fragments may mix with the solution when using glass ampule injection. Extra caution is required when administering to children and the elderly. This medication should not be administered to patients with a history of allergy or hypersensitivity to cimetidine or any other ingredients. It is also not used in patients taking dofetilide due to an increased risk of cardiac arrhythmias. Patients with impaired kidney or liver function, those with a history of drug hypersensitivity, elderly patients, children under 19 years, and patients undergoing hemodialysis require careful management including dose adjustment or dosing interval adjustment when administering this drug. This medication may mask symptoms of gastric cancer; therefore, it should only be used after confirming malignancy. Additionally, ulcer patients with Helicobacter pylori infection should undergo concurrent bacterial eradication therapy. Various side effects may occur during treatment with this drug, including decreased blood cell count, liver function abnormalities, kidney function decline, allergic reactions, gynecomastia, gastrointestinal symptoms, neurological disturbances, and skin reactions, and immediate consultation with medical personnel is advised if symptoms occur. Elderly patients and those with renal failure should pay particular attention to neurological side effects such as confusion or seizures. This medication can interact with several other drugs, so patients should inform healthcare providers of any concurrent medications, and dosage adjustments or discontinuation may be necessary. Women who are pregnant or may become pregnant should carefully consider the benefits and risks of using this drug, and breastfeeding women are advised to discontinue breastfeeding. The safety for pediatric patients has not been sufficiently established, so it should only be administered if absolutely necessary. Elderly patients may retain the drug in their body for a longer time due to diminished kidney function; therefore, they should use a reduced dosage or increase the dosing intervals. In cases of overdose, serious side effects such as respiratory depression may occur, necessitating immediate emergency measures. When used as an injection, rapid intravenous injection should be avoided, and slow infusion is recommended to reduce the risk of side effects. This medication should be stored out of reach of children, and transferring it to other containers should be avoided as it may lead to quality degradation or accidents.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reactions. Blood disorders resulting in leukopenia, granulocytopenia, agranulocytosis, thrombocytopenia, pancytopenia, aplastic anemia, immune hemolytic anemia. Liver abnormalities resulting in jaundice, hepatitis, elevated AST and ALT, hepatic fibrosis. Kidney abnormalities resulting in acute renal failure, interstitial nephritis, urinary retention, increased BUN. Hypersensitivity reactions leading to shock.

Mild side effects

• Fatigue
• fever
• generalized heat sensation
• dysuria
• myalgia
• arthralgia
• pancreatitis
• alopecia
• gynecomastia
• excessive milk secretion

This medication is sensitive to light and should be stored in a dark place. Additionally, avoid extremely hot or cold environments, and it is advisable to store at room temperature between 1 and 30 degrees Celsius.

Appearance

Pale green, round tablet

Package unit

500 tablets/bottle