Imetina 200 mg (Cimetidine)

Adult dosage

Adults: For cimetidine, 400 mg orally twice a day (morning, bedtime) or 800 mg once a day (at bedtime). Additionally, it can be administered as 300 mg orally four times a day (after meals, bedtime). It can be increased to 400 mg four times a day (after meals, bedtime) (a total of 1.6 g). However, for the improvement of gastric mucosal lesions (erosion, bleeding, redness, swelling) in the following conditions: acute gastritis and acute exacerbations of chronic gastritis, administer 200 mg twice a day or 400 mg once a day.

Children's dosage

Children: Administer divided oral doses of 20-40 mg per kilogram of body weight per day.

This medication may contain glass fragments when using ampoule injections; therefore, care should be taken when cutting the injection container. Extra caution is required, especially when used by children and elderly patients. Patients with a history of allergic reactions to cimetidine or any other components of this medication, or those taking dofetilide should not use it. There is an increased risk of cardiac arrhythmias when used with dofetilide. Patients with impaired kidney or liver function, those with a history of drug allergies, elderly patients, children under 19 years of age, and patients undergoing hemodialysis should use this medication cautiously. Particularly, it is advisable for hemodialysis patients to administer this medication after dialysis. This medication may mask symptoms of gastric cancer, so it should only be used after confirming that it is not gastric cancer, and patients with Helicobacter pylori infection and gastric/duodenal ulcers require bacterial eradication therapy. When taking this medication, various side effects such as decreased blood cell count, liver dysfunction, renal impairment, allergic reactions, endocrine disorders, gastrointestinal symptoms, neurological abnormalities, cardiac issues, skin disorders may occur, so if any unusual symptoms arise, immediate consultation with a physician is recommended. During treatment, the progress of the disease should be closely monitored, and only the minimum required dose should be used. If there is no effect, it is advisable to switch to other treatments. In particular, elderly patients or those with a history of peptic ulcers should be monitored regularly. This medication has many drug interactions, and dosing adjustments or drug holidays may be necessary for other medications being taken concurrently, so patients should inform about any medications they are taking. Women who are pregnant or may become pregnant should carefully weigh the risks and benefits of using this medication, and breastfeeding women are advised to discontinue breastfeeding. The safety for children has not been established, so it should only be used when absolutely necessary, and elderly patients may require dose adjustments due to diminished renal function which may increase drug concentration. In case of overdose, serious symptoms such as respiratory depression may occur, so appropriate medical treatment should be sought immediately at a hospital. When using injections, there is a risk of arrhythmias or blood pressure drops due to rapid intravenous administration, so slow infusion is necessary. This medication should be stored out of the reach of children, and transferring it to other containers may lead to degradation of quality or accidents, so caution is needed.

Serious side effects

• Urticaria
• severe swelling
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• shock
• anaphylaxis-like reaction
• generalized rash
• respiratory distress

Mild side effects

• Leukopenia
• agranulocytosis
• thrombocytopenia
• pancytopenia
• generalized malaise
• weakness
• subcutaneous hemorrhage
• mucosal hemorrhage
• fever
• immune hemolytic anemia

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. Proper storage like this helps to maintain the efficacy of the medication for a longer duration.

Appearance

Light green film-coated tablet

Package unit

30, 600 tablets/bottle