Medication info
Krabactor Tablets (Levofloxacin Hemihydrate)

Krabactor Tablets (Levofloxacin Hemihydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›100mg / 1 tablet
Manufacturer / importer
이연제약(주)
Appearance
Yellow round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201307960 · Approved 2013.07.02 · Insurance code 658602800

Summary

Main use
Treatment of complicated skin and soft tissue infections, secondary infections in chronic respiratory diseases, etc.
Who takes it
Adults
Adult dose
The usual adult dosage of levofloxacin is 100 mg taken orally 2 to 3 times a day. For patients with severe conditions or insufficient efficacy, it is administered as 200 mg 3 times a day. The dosage may be adjusted according to age and symptoms.

Ingredients

Manufacturer
이연제약(주)

Efficacy & effects

Treatment of complicated skin and soft tissue infections, secondary infections in chronic respiratory diseases, etc.

  • Complicated skin and soft tissue infections
  • chronic bronchitis
  • diffuse panbronchiolitis
  • secondary infections of chronic respiratory diseases
  • community-acquired pneumonia
  • bronchiectasis (infections)
  • acute pyelonephritis
  • cystitis
  • prostatitis
  • gonococcal urethritis
  • non-gonococcal urethritis
  • epididymitis
View approved original text

This drug is effective against various bacteria, particularly targeting harmful organisms such as Staphylococcus, Streptococcus, Pneumococcus, Neisseria gonorrhoeae, and Escherichia coli. It is used to treat complicated infections of the skin and soft tissues, as well as secondary infections in respiratory diseases like chronic bronchitis and community-acquired pneumonia. It is also effective for urinary tract infections, including pyelonephritis, cystitis, prostatitis, and urethritis, as well as gastrointestinal infections like bacterial dysentery and gastroenteritis. Additionally, it can be applied to infections in various organs including pelvic inflammatory disease in women, eye infections such as blepharitis and corneal ulcers, otitis media, sinusitis, and periodontal disease. This drug is also used for treating infections in the hepatobiliary system like cholecystitis and cholangitis, and, as a fluoroquinolone, it should be prescribed with caution when no alternative treatments are available due to serious adverse reaction risks. Overall, it is effectively used for treating a variety of bacterial infections.

How to take

Adult dose

The usual adult dosage of levofloxacin is 100 mg taken orally 2 to 3 times a day. For patients with severe conditions or insufficient efficacy, it is administered as 200 mg 3 times a day. The dosage may be adjusted according to age and symptoms.

Precautions

This drug is a fluoroquinolone antibiotic used for treating bacterial infections. Symptoms such as tendonitis or tendon rupture, peripheral neuropathy, and central nervous system abnormalities may occur while taking this drug, and you must stop taking it immediately if these symptoms appear. Patients with myasthenia gravis may experience worsening symptoms when using this drug, so it should not be used. Caution is advised for elderly patients, those with impaired renal function, and those taking corticosteroids due to an increased risk of tendon rupture. Additionally, this drug should not be administered to children, adolescents under 18, pregnant women, breastfeeding mothers, or patients with epilepsy. There is a risk of seizures while taking this drug, so patients with a history of seizures or central nervous system disorders should use it with caution. Allergic reactions, severe allergic reactions, and photosensitivity reactions may occur, so it is important to avoid sun exposure and stop taking the drug immediately if any unusual symptoms occur. This drug can cause side effects such as dizziness, drowsiness, and visual disturbances, which may affect driving or operating machinery. Moreover, it can cause adverse reactions in various organs such as the liver, kidneys, blood, and skin, and consultation with a healthcare professional is advised if any unusual symptoms occur. This drug may interact with other medications, so you must inform your healthcare provider of any medications you are currently taking, especially if they include hypoglycemic agents, anticoagulants, or antacids. In cases of overdose, central nervous system symptoms and heart abnormalities may arise, and you should visit a medical institution for appropriate treatment immediately. Finally, this drug has not established safety in growing children, and dosage adjustments may be necessary for the elderly due to decreased renal function.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, clamminess, pallor, hypotension, respiratory distress, chest constriction, a sense of pressure in the chest, hypotensive shock, seizures, loss of consciousness, numbness, vascular edema, airway obstruction, hives, rapid heartbeat, dysphagia, severe allergic reactions, severe rash with high fever, blisters, skin peeling, painful mucous membranes in the mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing.

Mild side effects

  • Nausea
  • diarrhea
  • vaginitis
  • insomnia
  • abdominal pain
  • bloating
  • itching
  • dizziness
  • rash
  • dyspepsia
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  • stomatitis
  • glossitis
  • dry mouth
  • constipation
  • vomiting
  • genital itching
  • headache
  • neurosis
  • erythematous rash
  • decreased appetite
  • drowsiness
  • excitement
  • thirst
  • tremors
  • allergic reactions
  • palpitations
  • QT interval prolongation
  • arrhythmia
  • increased BUN and serum creatinine
  • elevated liver enzyme levels (AST/ALT)
  • ALP
  • γ-GTP
  • and total bilirubin.

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container to prevent air intrusion and kept at room temperature between 1 degree and 30 degrees Celsius. This storage method helps maintain the efficacy of the medication.

Appearance and packaging

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.