Shuclaric 500 mg (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) per dose twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer this drug to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this drug per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug 3 times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, it should not be administered to patients who have allergies to any of its components or have had hypersensitivity reactions to similar classes of antibiotics. Patients taking certain medications or having heart diseases, liver dysfunctions, or severe kidney dysfunctions should not use this medication or should do so with caution. It is safer not to take this medication during pregnancy or while nursing. When administering this medication, caution should be taken as various side effects such as allergic reactions, gastrointestinal issues, skin rashes, liver and kidney function abnormalities, and central nervous system symptoms may occur. In particular, patients with a history of heart disease should use this medication carefully, as cardiac side effects may arise. This medication has a high potential for drug interactions, so it is essential to inform healthcare professionals about any other medications being taken. Dosage adjustments may be necessary, so patients with impaired liver or kidney function should follow the doctor's instructions. Prolonged or repeated use may lead to resistant bacteria, so it is essential to administer this medication only for the required period. If gastrointestinal symptoms such as diarrhea or abdominal pain worsen during use, consult healthcare professionals immediately, and if severe allergic reactions occur, stop administration and seek emergency care. This medication contains lactose; therefore, patients with lactose intolerance should not use it. Use in the elderly or children, especially those under 12 years old, is limited and requires special caution.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, ageusia, anosmia, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, hepatic failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, increased LDH, increased ALP, elevated total bilirubin, anorexia, dark urine, itching, abdominal tenderness, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, increased serum myoglobin, increased urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute pancreatitis, increased amylase, elevated AST and ALT, leukopenia, thrombocytopenia, elevated ALT, elevated AST, increased γ-GTP, increased ALP, elevated LDH, increased total bilirubin, increased BUN, elevated serum creatinine, prolonged prothrombin time, elevated ALT, elevated AST, increased γ-GTP, increased ALP, elevated LDH, increased total bilirubin, increased serum alkaline phosphatase, increased blood lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, cardiac arrest, atrial fibrillation, ECG QT prolongation, ectopic beats, palpitations, ventricular fibrillation, vasodilation, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal stiffness, myopathy, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue

This medication is sensitive to light; therefore, it should be stored in a container that does not allow light. Additionally, to maintain its effectiveness, it is important to store it at cool room temperature, specifically between 15 to 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle