Sofia Tablet 10mg (Atorvastatin Calcium Hydrate)

Adult dosage

For hyperlipidemia treatment, the recommended initial dosage is 10 mg once a day. If greater LDL cholesterol reduction is needed, the initial dosage can be 20 mg or 40 mg once a day. Dosages should be administered within the range of 10 to 80 mg once a day, and personalized based on the therapeutic goals and patient response. Lipid levels should be monitored within 2 to 4 weeks of starting treatment or making dosage adjustments to adjust the dosage accordingly. The goal of the treatment is to reduce LDL cholesterol levels, so monitoring LDL cholesterol levels is recommended when assessing treatment response. If LDL cholesterol levels cannot be used, total cholesterol levels should be used for monitoring treatment responses. For patients with homozygous familial hypercholesterolemia, the recommended dosage is 10 to 80 mg once a day, used in conjunction with other lipid-lowering treatments (e.g., LDL apheresis) or when such treatments are not feasible. For pediatric patients (ages 10 to 17) with heterozygous familial hypercholesterolemia, the recommended initial dosage is 10 mg once a day, and the maximum recommended dosage is 20 mg once a day (clinical data on doses higher than 20 mg in this age group is not available). The dosage should be appropriately adjusted based on the recommended therapeutic goals for individual patients. Dosage adjustments should be made at intervals of 4 weeks or more. ○ For patients with renal impairment: Renal disease does not influence atorvastatin's plasma concentrations or LDL cholesterol lowering effect, so dosage adjustments are not necessary. ○ For elderly patients: The efficacy and safety for patients aged 70 years and older are comparable to those for adult patients.

Children's dosage

For pediatric patients (ages 10 to 17) with heterozygous familial hypercholesterolemia, the recommended initial dosage is 10 mg once a day, and the maximum recommended dosage is 20 mg once a day. The dosage should be adjusted based on the therapeutic goals for the patient.

This medication may cause muscle-related symptoms, so if there is severe muscle pain or weakness, or a significant increase in creatine kinase levels, discontinue use immediately and consult a doctor. Patients with impaired liver function should not take this medication and should undergo regular liver function tests. Women who are pregnant, may become pregnant, or are nursing should not take this medication. Patients with a history of alcohol abuse or liver disease should use this medication with caution and adjust the dose under medical supervision if necessary. This medication may interact with other drugs, so it is essential to consult a doctor or pharmacist before taking it with certain antibiotics, antifungals, antivirals, some heart medications, antihypertensives, and antidiabetics. Children and individuals under the age of 10 should not take this medication, and long-term safety in adolescents under 18 is not established. Elderly patients are at higher risk for myopathy, so caution is needed during use, and any symptoms should be reported to healthcare providers immediately. In case of overdose, there is no specific antidote, and treatment should be symptomatic while closely monitoring for liver function and muscle damage. Taking this medication with grapefruit juice may increase blood levels of the drug, so it is advisable to avoid grapefruit juice. If symptoms such as muscle pain, weakness, fatigue, or fever occur during use, contact a doctor immediately for evaluation. This medication contains lactose, so patients with lactose intolerance should not take it. Keep this medication out of the reach of children and store it securely in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, respiratory issues, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and

Mild side effects

• Fatigue
• malaise
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. Doing so will help preserve the medication's effectiveness and prevent degradation.

Appearance

White, round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle