Clarithin Tablet (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) per dose twice daily; for severe infections, administer 500mg (potency) per dose twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, or rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine three times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be used in patients who are allergic to any of its components or have had hypersensitivity reactions to macrolide antibiotics. Patients with heart rhythm abnormalities or a history of ventricular arrhythmias should exercise particular caution when administering this drug. Patients with severely impaired liver or kidney function should use this medication cautiously, and dosage adjustments may be required. It is safest for pregnant or breastfeeding women to avoid taking this medication. This drug may cause severe side effects or drug interactions when taken with other specific medications, so individuals should inform their healthcare provider of any medications they are currently taking. If symptoms such as allergic reactions, severe diarrhea, skin rash, or difficulty breathing occur during treatment, discontinue use immediately and consult a medical institution. Care should be taken as prolonged or high-dose use may lead to hearing loss or tinnitus. It is important to regularly monitor liver and kidney functions while taking this medication to ensure there are no abnormalities. Additionally, caution should be exercised as dizziness or confusion may occur while driving or operating machinery. Children, the elderly, and immunocompromised patients may be more sensitive to the side effects of this drug, so they should take it according to their physician's guidance.

Shock, anaphylactic symptoms, dyspnea, seizures, flushing, rash, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, loss of appetite, constipation, tongue discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, chest X-ray abnormalities, eosinophilia, eosinophilic pulmonary infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, loss of appetite, jaundice, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, myalgia, weakness, elevated CPK, increased myoglobin in blood and urine, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, lethargy, headache, dysgeusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute generalized exanthematous pustulosis, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactic reaction, angioedema, decreased appetite, insomnia, neuroexcitation, noise sensitivity, psychotic disorder, confusional state, abnormal dreams, movement disorder, peripheral vertigo, drowsiness, tremors, vestibular vertigo, hearing impairment, hearing loss, cardiac arrest, atrial fibrillation, ECG QT prolongation, occasional extrasystoles, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, abdominal bloating, acute pancreatitis, tongue discoloration, tooth discoloration, abnormal liver function tests, cholestasis, hepatitis, alanine aminotransferase elevation, aspartate aminotransferase elevation, gamma-glutamyltranspeptidase elevation, liver failure, hepatocellular jaundice, rash, hyperhidrosis, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura, muscle spasms, musculoskeletal stiffness, myopathy, elevated blood urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase levels, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, changes in mental state, compulsive behavior, hypokalemia, hypoxemia

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is advisable to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature. This helps to preserve the effectiveness of the medication.

Appearance

Yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle