Clasta Tablets (Clarithromycin)

Adult dose

Adults: The usual dose is 250mg (potency) of clarithromycin twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily for 14 days with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be used in patients allergic to certain ingredients. Patients who have had allergies to antibiotics similar to this drug should also avoid administering it. Taking this medication with certain drugs can lead to heart rhythm abnormalities, so patients on those medications should not use this drug. It is advisable not to use this medication in patients with heart rhythm abnormalities or severely impaired liver function. Use of some formulations of this drug is restricted in patients with severely impaired kidney function. Pregnant or breastfeeding women should not take this medication; if unavoidable, breastfeeding should be discontinued. Patients with central nervous system infections or certain cardiac and renal conditions should use this medication cautiously. This drug can cause various side effects, so if any unusual symptoms such as rash, difficulty breathing, severe abdominal pain, diarrhea, hearing impairment occur, discontinue use immediately and consult a doctor. Prolonged or high-dose use can lead to tinnitus or hearing loss, so caution is required. Because of many drug interactions, if you are currently taking other medications, be sure to inform medical personnel, especially when combined with certain antibiotics, heart medications, anticoagulants, or antidiabetic drugs. Patients with impaired liver or kidney function may require dose adjustments. To prevent the development of antibiotic-resistant bacteria, it is important to administer this medication only for the necessary duration after sensitivity testing. Caution is advised while driving or operating machinery during treatment, as dizziness or confusion may occur. In case of overdose, gastrointestinal disturbances or psychiatric symptoms may appear, and immediate treatment should be sought. Store in a cool place, avoiding direct sunlight, and it is advisable not to refrigerate.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, general malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, hearing impairment, vomiting, purpuric rash, acute generalized exanthematous pustulosis, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactoid reaction, vascular edema, reduced appetite, insomnia, nervousness, noise sensitivity, psychotic disorder, confusion state, abnormal dreams, mania, movement disorders, non-vertiginous dizziness, drowsiness, tremor, vertiginous dizziness, hearing disorder, hearing loss, cardiac arrest, atrial fibrillation, ectopic beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, acute pancreatitis, tongue discoloration, sweating, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura, muscle cramps, musculoskeletal rigidity, myopathy, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This drug should be stored in a closed container to prevent contact with air or moisture, preferably between 1 to 30 degrees Celsius. This way, the medication's effectiveness can be safely maintained.

Appearance

Yellow, rectangular, film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle