Clarithromycin 500mg (Clarithromycin)

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

○ Children 12 years of age and older: Same as adults. ○ For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in patients with certain medications or health conditions. For example, those who are allergic to this drug, have certain heart conditions, or have severely impaired liver or kidney function, and women who are pregnant or breastfeeding should not take this drug. Since this drug is primarily metabolized in the liver, caution should be exercised in patients with poor liver function or those with moderately to severely impaired kidney function, and dosage adjustments may be necessary. Patients with heart disease should be careful as this medication may pose a risk of heart rhythm abnormalities. This drug may interact with other antibiotics or multiple medications, so it is essential to inform your doctor or pharmacist if you are taking other medications. If you experience an allergic reaction or severe side effects (e.g., difficulty breathing, rash, severe abdominal pain, persistent diarrhea, etc.) while taking this medication, stop taking it immediately and consult medical personnel. This drug can alter the intestinal bacterial balance, potentially causing diarrhea or colitis, so it should be discontinued if severe diarrhea or blood in stool occurs. Caution is warranted for prolonged or excessive use, as this can lead to side effects such as hearing disturbances, tinnitus, hypoglycemia, etc. It is advisable to avoid this medication during pregnancy or while breastfeeding, and women who are breastfeeding may need to discontinue breastfeeding. Special caution is needed for children, the elderly, and patients with weakened immune systems, as careful consideration of dosages and duration of treatment is required. This medication may affect driving or machinery operation abilities, so if dizziness or confusion occurs after taking it, caution should be exercised. Overdosage may lead to gastrointestinal disturbances or central nervous system abnormalities, so adherence to prescribed dosages is necessary. This medication should be stored away from light and kept at room temperature, between 15 to 30 degrees Celsius, with refrigeration not recommended.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, epigastric pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste alteration, anorexia, constipation, fecal discoloration, colonic membrane colitis, hemorrhagic colitis, fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, orientation disturbance, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, phlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urine discoloration, vasodilation, asthma, nosebleeds, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura

This medication is sensitive to light and should be stored in a tightly closed container that blocks light. It is also recommended to maintain the medication at room temperature between 15 to 30 degrees Celsius.

Appearance

Yellow oval film-coated tablets with a vanilla flavor

Package unit

30 tablets/bottle, 100 tablets/bottle