Megatab (Terbinafine Hydrochloride)

Adult dose

As terbinafine: 125 mg once, twice daily, or 250 mg once daily. Treatment duration may vary based on the condition: 1) Dermatophytosis - Athlete's foot (interdigital, plantar/moccasin-type): 2 to 6 weeks - Tinea corporis: 2 to 4 weeks - Tinea cruris (jock itch): 2 to 4 weeks 2) Onychomycosis - Typically treated for 6 weeks to 3 months. Infections of the fingernails or relatively small toes may require shorter treatment durations, while fingernail treatment duration is generally sufficient at 3 months, although some patients might need treatment for 6 months or more depending on their nail growth rate.

Child dose

Administer to children over 2 years of age. Tinea capitis: 4 weeks 1) Under 20 kg (under 5 years): 62.5 mg once daily. Due to limited experience, the benefits and risks of treatment should be carefully considered.

This medication is not recommended for patients with chronic liver disease or active liver disease. Before taking this drug, be sure to check for any history of liver disease and to undergo regular liver function tests. If liver function test results become elevated, discontinue this medication immediately. During treatment, if you experience persistent nausea, loss of appetite, fatigue, vomiting, pain in the upper right abdomen, jaundice (yellowing of the skin or eyes), dark urine, diarrhea, or other symptoms without reason, inform your doctor immediately. This medication rarely causes serious liver damage; if liver function worsens, treatment should be stopped. Patients with an allergy to this drug or any of its ingredients, those with blood disorders or severe renal failure, children under 2 years of age, and breastfeeding women should not take this medication. Patients with impaired renal function, the elderly, and children under 20 kg should use this medication with caution. This drug may rarely cause serious skin reactions; thus, if skin rashes or abnormal symptoms occur, use should be discontinued immediately. This drug is predominantly metabolized in the liver, so patients with impaired liver and renal function require special care. While taking this medication, you should undergo regular liver function tests and blood tests, and consult a doctor immediately if any abnormal symptoms arise. This medication should only be used for fungal infections that are difficult to treat topically; it is advisable to avoid driving or operating machinery if symptoms such as dizziness occur. Interactions may occur when combined with other medications, so inform your doctor or pharmacist of any medications you are currently taking. Particularly, care should be taken with drugs metabolized in the liver, including dosage adjustments. Women who are pregnant or may become pregnant should use this medication carefully, and breastfeeding women should discontinue breastfeeding while taking it. In case of overdose, symptoms such as headache, nausea, abdominal pain, and dizziness may appear, and medical attention should be sought immediately. Store this medication out of reach of children and protect it from direct sunlight at room temperature.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, high fever along with severe rash, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, abnormal breathing accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Fatigue
• nausea
• loss of appetite
• vomiting
• rash
• itching
• photosensitivity reactions
• headache
• taste disturbances
• dizziness

This medication should be stored in a tightly closed container to prevent air ingress, ideally at temperatures between 1 and 30 degrees Celsius. Proper storage will maintain the drug's effectiveness and prevent degradation.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle