Medication info
Dioval Tablet 160 mg (Valsartan)

Dioval Tablet 160 mg (Valsartan)

Prescription medicationTablet경구
Ingredient · strength
Valsartan›160mg / 1 tablet
Manufacturer / importer
제일약품(주)
Appearance
Oval film-coated tablet, orange with a grayish tint
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201207082 · Approved 2012.10.08 · Insurance code 645403800

Summary

Main use
Treatment of essential hypertension and heart failure (ACE inhibitor intolerance), reduction of mortality risk after myocardial infarction.
Who takes it
Adults · Children
Adult dose
1. Essential Hypertension - Take with water during or between meals. - It is recommended to take it at the same time every day (e.g., in the morning). - A dose of 80 mg orally once daily is recommended. - If blood pressure is not well controlled, the dose may be increased to 160 mg once daily, and if necessary, to a maximum of 320 mg. - Elderly patients (75 years and older) should start with 40 mg once daily.
Child dose
Safety and efficacy in individuals under 18 years of age have not been established.

Ingredients

Manufacturer
제일약품(주)

Efficacy & effects

Treatment of essential hypertension and heart failure (ACE inhibitor intolerance), reduction of mortality risk after myocardial infarction.

  • Essential hypertension
  • heart failure
  • left ventricular failure
  • left ventricular systolic dysfunction
View approved original text

This medication is used for the treatment of essential hypertension. Additionally, it helps improve symptoms in heart failure patients who are intolerant to ACE inhibitors. It is also used to reduce the risk of death in patients with left ventricular failure or dysfunction after myocardial infarction. Therefore, it is effective for blood pressure control and improvement of cardiac function.

How to take

Adult dose

1. Essential Hypertension - Take with water during or between meals. - It is recommended to take it at the same time every day (e.g., in the morning). - A dose of 80 mg orally once daily is recommended. - If blood pressure is not well controlled, the dose may be increased to 160 mg once daily, and if necessary, to a maximum of 320 mg. - Elderly patients (75 years and older) should start with 40 mg once daily.

Child dose

Safety and efficacy in individuals under 18 years of age have not been established.

Precautions

This drug can cause severe harm to the fetus when taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication. Patients with severe liver impairment, severe renal impairment, hereditary angioedema, and certain other conditions should not take this medication. Special caution is needed for elderly patients, patients with hyperkalemia, and patients with mild to moderate liver dysfunction, and dosage may need adjustment. This medication can have a strong blood pressure-lowering effect, which may cause dizziness or fainting due to severe hypotension when taken for the first time, so caution is required. Particularly for patients taking diuretics or those who are depleted of fluids or sodium, the risk of hypotension is high, so their condition should be closely monitored at the beginning of treatment. When taken in conjunction with potassium-sparing diuretics or potassium supplements, potassium levels in the blood can rise dangerously, so caution is needed. Co-administration with non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the hypotensive effect or worsen renal function, so renal function should be regularly monitored when taken together. When taken with lithium preparations, lithium levels may increase and toxicity can occur, so blood lithium levels should be regularly checked. This medication can affect liver or kidney function, so it is important to regularly conduct blood tests to check renal function and electrolyte status. Dizziness or drowsiness may occur, so caution should be exercised when driving or operating machinery. While taking this medication, side effects such as headache, dizziness, fatigue, cough, and diarrhea may occur, and in severe cases, a doctor should be consulted immediately. Safety and efficacy in children and adolescents have not been established, so use is not recommended. Overdose can lead to severe hypotension and decreased consciousness, requiring immediate emergency treatment. This medication should be stored out of the reach of children and transferring it to another container should be avoided, as it may cause quality deterioration or accidents.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, breathing difficulties, cold sweats, paleness, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), extreme drowsiness, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

  • Headache
  • dizziness
  • viral infections
  • upper respiratory infections
  • cough
  • diarrhea
  • fatigue
  • rhinitis
  • sinusitis
  • back pain
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  • abdominal pain
  • nausea
  • pharyngitis
  • joint pain
  • hypotension
  • orthostatic dizziness
  • orthostatic hypotension
  • drowsiness
  • vomiting
  • constipation
  • thirst
  • loss of appetite
  • malaise
  • flushing
  • itching
  • serum sickness
  • vasculitis
  • fainting
  • epistaxis
  • hepatitis
  • arrhythmias
  • intestinal vascular swelling
  • hypoglycemia
  • rhabdomyolysis
  • agranulocytosis
  • leukopenia
  • thrombocytopenia.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a container that is well-sealed to prevent deterioration of the contents. Additionally, it should be kept in a cool place below 30 degrees Celsius to maintain its effectiveness, avoiding heat and humidity.

Appearance and packaging

Appearance

Oval film-coated tablet, orange with a grayish tint

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.