Clarithron Tablet 250 mg (Clarithromycin)

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) per dose twice daily; for severe infections, administer 500mg (potency) per dose twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections: Administer 500mg (potency) of this drug per dose twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and administer omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

This medication should not be administered to certain patients. Patients allergic to any additives contained in this drug or those who have had hypersensitivity reactions to similar classes of antibiotics should not use it. Additionally, it should not be given to patients with severe impairment of liver and kidney function, or to pregnant and breastfeeding women. Caution should be exercised when using this drug in patients with mild liver or kidney impairment, heart disease, elderly patients, etc. Care should also be taken with drug interactions when taken with other antibiotics, and cautious administration is needed if there is a history of allergies. While taking this medication, severe allergic reactions, skin rashes, gastrointestinal issues, liver and kidney dysfunction, neurological symptoms, etc., may occur. If such symptoms appear, discontinue the medication immediately and consult a doctor. This medication can affect the balance of intestinal bacteria, potentially leading to symptoms such as diarrhea or colitis, so consult a doctor if persistent diarrhea occurs. This medication can interact with various drugs, so be sure to inform your doctor or pharmacist if you are taking any other medications. Special care should be taken with heart-related medications, anticoagulants, diabetes medications, etc., regarding changes in blood concentration or side effects. It is safest for pregnant or breastfeeding women to avoid taking this medication, and if necessary, breastfeeding should be stopped. Children or elderly patients may have different bodily functions, so careful monitoring and possible dose adjustments are required when using this drug. In case of overdose, gastrointestinal disturbances or neurological symptoms may occur, so if suspected, visit the hospital immediately for appropriate treatment. This medication should be stored at room temperature away from direct sunlight, and not refrigerated.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, hematochezia, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, increased total bilirubin, anorexia, dark-colored urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, oliguria, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, auditory dysfunction, hypoglycemia, purpuric rash, acute generalized pustular psoriasis, muscle cramps, musculoskeletal rigidity, myopathy, elevated blood creatinine, elevated blood urea nitrogen, nephritis, phlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication should be stored in a tightly sealed container that blocks light, preferably at room temperature between 15 and 30 degrees Celsius. Storing it this way preserves the medication's efficacy for a longer time.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle