Alendros Plus D Tablet

Adult dose

Once a week, take 1 tablet (70 mg/2800 IU or 70 mg/5600 IU) in the morning with a sufficient amount of water at least 30 minutes before consuming food, drinks, or other medications. This medication should be taken immediately upon waking to ensure it reaches the stomach quickly and reduces the possibility of esophageal irritation by swallowing it with a sufficient amount of water (170–230 mL). After taking it, do not lie down for at least 30 minutes, and avoid taking it before bedtime or upon waking. Failure to adhere to this regimen may increase the risk of esophageal adverse reactions. Patients with insufficient dietary intake of calcium and vitamin D should take supplements.

Child dose

Pediatric and adolescent (under 18 years): Safety and efficacy have not been established for children and adolescents.

This medication may irritate the upper gastrointestinal mucosa and can lead to esophageal adverse reactions such as esophagitis or esophageal ulcers. If such symptoms occur, discontinue use immediately and consult a doctor. Take this medication with plenty of water, and do not lie down for at least 30 minutes after taking it. Patients with esophageal clearance problems or those who cannot sit or stand upright should not take this medication. This medication is also not administered to patients with low calcium concentrations or certain genetic metabolic disorders. During treatment, gastrointestinal symptoms, musculoskeletal pain, headaches, dizziness, dysgeusia, and other abnormal symptoms may occur, necessitating consultation with a doctor. In particular for osteoporosis patients, ensure adequate intake of calcium and vitamin D before and during the use of this medication and supplement if necessary. This medication may be hindered in absorption when taken with calcium supplements or antacids, and it should be spaced at least 30 minutes apart from other medications. Furthermore, caution should be exercised when used in conjunction with aspirin or nonsteroidal anti-inflammatory drugs due to an increased risk of gastrointestinal adverse reactions. It is administered during pregnancy only in special cases due to potential effects on the fetus, and usage during breastfeeding should also be approached with caution. It is not recommended for children or patients with severe renal insufficiency. In case of overdose, hypocalcemia and gastrointestinal irritation may occur, necessitating immediate contact with a medical institution for appropriate action. This medication should be stored out of reach of children and should not be transferred to another container.

Serious side effects

• Hives
• angioedema
• esophagitis
• esophageal erosion
• esophageal stricture
• esophageal perforation
• severe esophageal adverse reactions
• gastric ulcers
• duodenal ulcers
• localized osteonecrosis of the jaw

Mild side effects

Abdominal pain, nausea, dyspepsia, constipation, diarrhea, flatulence, gastroesophageal reflux, esophageal ulcer, vomiting, dysphagia, abdominal distension, gastritis, musculoskeletal (bone, muscle, or joint) pain, muscle cramps, headaches, dizziness, dysgeusia, rash, itching, hair loss, and rhinitis.

This medication is sensitive to air and moisture and should be stored in a container that is tightly sealed. Storage temperature should be maintained between 1 to 30 degrees Celsius, and it’s advisable to keep it in a cool place away from direct sunlight.

Appearance

White to pale white oblong tablets with KJ engraved on one side and a bone illustration on the other side.

Package unit

4 tablets/PTP