Onepharm Injection (Nephepam Hydrochloride)

Adult administration

Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer intravenous injections slowly over at least 15 minutes. After administration, it is preferable to have the patient lie still and rest for 15-20 minutes. If administered in an infusion solution such as an electrolyte or glucose solution, administer 30mg over 4 hours or 40mg over 6-8 hours, in proportion to the administration time. It is recommended to avoid mixing this medicine with other medicines for injection. The dosage may be adjusted appropriately according to age and symptoms.

This medication is in injection form, so care must be taken when cutting the glass ampoule during use. If glass fragments get mixed in, it can be harmful to the body, so it should be handled carefully. This medication should not be used in patients with epilepsy or myocardial infarction, in individuals taking certain antidepressants like MAO inhibitors, and in those allergic to this drug or its ingredients. It should also be avoided in children under 15, in those with a history of seizures or urinary retention due to urethral and prostate issues, and in patients with closed-angle glaucoma. Elderly patients, pregnant or breastfeeding women, and individuals taking anticholinergic drugs should be especially cautious when using this medication. Using this drug may result in various side effects such as loss of appetite, nausea, drowsiness, dizziness, palpitations, dry mouth, urinary retention, pain at the injection site, headache, blurred vision, fatigue, and irritability. Rarely, sleep disturbances, hallucinations, seizures, and allergic reactions may occur. Side effects can vary with medication dosage, and most will gradually disappear with repeated use. Although this drug is used for treating inflammation or pain, it does not treat the underlying cause, so it should be used appropriately based on symptoms. In cases of inflammation caused by infection, it should be used in conjunction with antibacterial or antifungal medications, and the patient’s condition should be closely monitored. This medication may be affected by liver and kidney function, so those with issues in these organs should exercise caution. It can also cause drowsiness or impaired concentration, so it is advisable to avoid using it when driving or operating machinery. When used in conjunction with other analgesics or certain neurological drugs, side effects may increase, so consultation with a physician is recommended. Its use is not recommended during pregnancy or lactation, and safety and efficacy have not been confirmed for children under 15. In case of overdose, immediate consultation with medical personnel is necessary, and careful observation of heart and respiratory status may require treatment. It is advisable not to mix this medication with other drugs for injection, and it should be stored in a sealed container that prevents air and moisture from entering. Keep out of reach of children in a cool, dry place, avoiding direct sunlight, and take care not to transfer to other containers.

• Loss of appetite
• gastrointestinal disorders
• nausea
• drowsiness
• vomiting
• excessive sweating
• dizziness
• tachycardia
• palpitations
• thirst

This drug should be stored in a sealed container to prevent air and moisture from entering. It is best to maintain a storage temperature between 1 and 30 degrees Celsius. Storing it this way will help preserve its efficacy and safety.

Appearance

A colorless and odorless transparent liquid contained in a colorless transparent ampoule injection

Package unit

20 ampoules/box (2 milliliters/1 ampoule)