Basotrol Tablet 6.25 mg (Carvedilol)

Adult dose

Do not increase the dose or discontinue this medication without a doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first two days, administer 12.5mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25mg twice daily. The maximum dose per administration is 25mg, and the maximum daily dose is 50mg. 2) Elderly patients In some elderly patients, 12.5mg once daily may provide a sufficient effect. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first two days, administer 12.5mg of this medication twice daily orally, then administer 25mg twice daily orally. 2) The usual dose is 25mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased to 50mg twice daily. 3. Congestive heart failure Before initiating treatment with this medication, the patient should be stable on the standard treatment regimen already being administered (the conventional treatment regimen for chronic heart failure, which includes an ACE inhibitor, a diuretic, and usually a digitalis preparation). In addition, fluid retention should be minimized before initiating treatment with this medication. 1) In general, the initial dose is 3.125mg of this medication twice daily orally for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25mg twice daily and administer for 2 weeks, then increase to 12.5mg twice daily and administer for 2 weeks, and then increase to 25mg twice daily. 2) Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose the patient can tolerate. 3) The minimum effective dose is 6.25mg twice daily, and the maximum dose is 25mg twice daily for patients weighing 85kg or less, and 50mg twice daily for patients weighing more than 85kg. 4) To control the rate of absorption, it is recommended to take this medication with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be administered to certain patients. For example, patients who are allergic to this drug or its components, or have conditions such as cardiogenic shock, heart conduction abnormalities, or pulmonary heart disease may experience exacerbation of symptoms. Additionally, patients with respiratory diseases like asthma or chronic obstructive pulmonary disease may experience bronchoconstriction and worsening symptoms upon using this medication. Caution is also necessary for patients with diabetic ketoacidosis or severely compromised heart function. Women who are pregnant or breastfeeding should not take this medication, and patients with hereditary lactose intolerance should avoid it. Moreover, diabetic patients, the elderly, individuals with weakened kidney or liver function, and those with very low blood pressure need to use this medication cautiously. This drug may affect heart rate and blood pressure, so patients with heart disease or difficult-to-control blood pressure should also exercise caution. While taking this medication, symptoms such as dizziness, headache, and fatigue may occur, and rarely, heart rate may slow excessively or heart failure symptoms may worsen. Additionally, liver dysfunction, skin rashes, and symptoms of hypoglycemia may appear, so any unusual symptoms should be reported to a doctor immediately. For long-term use, regular monitoring of heart function, blood pressure, and blood tests is necessary, and abruptly stopping treatment may worsen heart problems; thus, the dosage should be reduced gradually under a doctor’s guidance. When taken with other drugs, there may be interactions, so all medications being taken should be disclosed to a physician or pharmacist, especially when combined with antihypertensives, heart medications, antidiabetics, sedatives, or antidepressants. Women who are pregnant or breastfeeding should avoid this medication, and especially in children and adolescents, where safety has not been established, it is advisable not to use it. In case of overdose, there is a risk of severe hypotension, decreased heart rate, and respiratory distress, so immediate contact with medical personnel and appropriate treatment is necessary. Lastly, since this medication may discolor due to light exposure, it should be stored in a light-blocking container and kept out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medicine is sensitive to light and should be stored in a container that blocks light. To maintain the effectiveness of the drug, it is important to store it at room temperature, that is, between 1 degree and 30 degrees Celsius.

Appearance

Pale yellow round tablet

Package unit

100 tablets/PTP