Nazeron Injection 0.3 mg (Ramosetron Hydrochloride)

Adult dosage

Administer 0.3 mg of Ramosetron Hydrochloride intravenously once daily. If the effect is insufficient, the same dose may be administered additionally. However, do not exceed 0.6 mg in a single day. Adjust the dosage appropriately according to the symptoms.

This medication is in injection form and should be used with caution when cutting the glass ampule. The presence of glass fragments can cause side effects, especially when used for children or the elderly. Individuals with allergies to this drug or its components should never use it. Patients taking other serotonergic medications, such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), should use this drug with caution and follow their doctor's instructions. Rarely, serious allergic reactions such as shock or anaphylaxis may occur, so if symptoms appear, administration should be stopped immediately and medical personnel should be informed. There have been reports of seizure-like symptoms; patients with a history of seizures should use caution. Side effects may include headache, diarrhea, itching, rash, abnormal liver function, and others, and any unusual symptoms should be discussed with healthcare professionals. This drug is primarily metabolized in the liver, so patients with impaired liver function or those using certain drugs should be cautious as blood concentration may increase, raising the risk of side effects. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of using this drug, and it is recommended to discontinue breastfeeding if using this medication. The safety of this drug in pediatric patients has not been sufficiently established, so special caution is necessary when using it in children. Elderly patients may have diminished bodily functions and should be closely monitored during administration, and immediate action should be taken in case of adverse reactions. This medication may cause problems if mixed with certain solutions; therefore, it should not be mixed, and it is advisable to cleanly cut the ampule with an alcohol swab or similar item. Lastly, animal studies have reported potential effects on fetal growth, so care is needed when used during pregnancy.

Serious side effects

Shock, anaphylaxis-like symptoms (chest tightness, difficulty breathing, asthma), seizure-like episodes

Mild side effects

Headache, feeling of heaviness in the head, diarrhea, constipation, increased BUN, elevated blood creatinine, abnormal liver function (elevated AST, elevated ALT, elevated r-GTP, elevated bilirubin), sensation of warmth, belching, heat sensation in the head, tingling of the tongue, insomnia, rash, itching, redness, urticaria, hypersensitivity reactions

Store this medication in a tightly sealed container to protect it from air and light exposure. Additionally, it should be kept at room temperature away from direct sunlight to maintain its effectiveness.

Appearance

A colorless, clear liquid in a brown glass ampule for injection

Package unit

2 mL/ampule, 2 mL/ampule X 5