Medication info
Pregabalin 150mg (Pregabalin)

Pregabalin 150mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›150mg / 1 capsule
Manufacturer / importer
(주)동구바이오제약
Appearance
A hard capsule with a white or light yellow powder inside, with a white cap and body.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201109293 · Notified 2011.10.31 · Insurance code 657305740

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunct for partial seizures in epilepsy, improvement of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication is administered orally, divided into two doses daily, regardless of meals. Neuropathic pain (peripheral and central): Initial dose of 150 mg daily, which may be increased to 300 mg daily based on response and tolerability after 3 days to 1 week, and if necessary, may be further increased up to a maximum daily dose of 600 mg. Epilepsy: Initial dose of 150 mg daily, which may be increased to 300 mg daily after 1 week.
Child dose
Administration for children under 12 years old and adolescents aged 12 to 17 is not recommended due to insufficient safety and efficacy data.

Ingredients

Manufacturer
(주)동구바이오제약

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunct for partial seizures in epilepsy, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used to alleviate peripheral and central neuropathic pain in adults. It can also be used as an adjunct for partial seizures in epilepsy, whether or not accompanied by secondary general symptoms. Additionally, it is effective for treating pain due to fibromyalgia. In summary, it is used for the treatment of peripheral and central neuropathic pain, adjunctive therapy for partial seizures in epilepsy, and for fibromyalgia treatment.

How to take

Adult dose

This medication is administered orally, divided into two doses daily, regardless of meals. Neuropathic pain (peripheral and central): Initial dose of 150 mg daily, which may be increased to 300 mg daily based on response and tolerability after 3 days to 1 week, and if necessary, may be further increased up to a maximum daily dose of 600 mg. Epilepsy: Initial dose of 150 mg daily, which may be increased to 300 mg daily after 1 week.

Child dose

Administration for children under 12 years old and adolescents aged 12 to 17 is not recommended due to insufficient safety and efficacy data.

Precautions

This medication may increase the risk of suicidal thoughts or behavior, so one should monitor for mood changes or abnormal behavior while taking it. It should not be taken by individuals with hypersensitivity to the drug or with certain genetic disorders such as lactose intolerance. Diabetic patients should be cautious, as weight gain may require adjustments in diabetes control medications. If symptoms of angioedema occur, discontinue use immediately and consult a healthcare professional. Elderly patients should be particularly careful at the beginning of treatment due to the risk of dizziness or drowsiness causing falls or injuries. Blurred vision or changes in eyesight may occur, and if these symptoms appear, discontinuation of the medication should be considered. Sudden discontinuation of this medication may result in withdrawal symptoms such as insomnia, headache, and anxiety, so it should be tapered off gradually in consultation with a healthcare professional. Patients with a history of mental illness or substance abuse should be especially cautious due to the risk of drug misuse. Patients with reduced renal function may require dosage adjustments. Patients with heart disease should be aware of the risk of congestive heart failure. If taken in conjunction with opioid analgesics, side effects due to central nervous system depression may be exacerbated. Patients with impaired respiratory function or elderly individuals may require dosing adjustments due to the risk of severe respiratory depression. Pregnant women, especially in the first trimester, should consult a healthcare provider before use due to the risk of fetal malformations. Breastfeeding women should consider stopping breastfeeding or the medication, as this drug may be passed to breast milk. For activities such as driving or operating machinery, it is advisable to avoid until any dizziness or drowsiness has resolved after taking this medication. Severe skin reactions may rarely occur, so if any unusual symptoms such as rashes or swelling develop, discontinue use immediately and inform a healthcare provider. In the case of an overdose, symptoms such as drowsiness, confusion, depression, and seizures may occur, necessitating immediate medical attention, and blood dialysis may be required if necessary. This medication should be stored out of the reach of children and not transferred to other containers for safety.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory anomalies accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination issues.

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • disorientation
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • hyperesthesia
  • agitation
  • anxiety
  • mood swings
  • emotional flattening
  • emotional elevation
  • difficulty finding appropriate terms
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • coordination issues
  • balance disorders
  • memory loss
  • attention deficit
  • memory deficit
  • tremors
  • speech disturbances
  • sensory abnormalities
  • sensory loss.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is best to maintain a storage temperature between 15 and 30 degrees Celsius.

Appearance and packaging

Appearance

A hard capsule with a white or light yellow powder inside, with a white cap and body.

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.