Medication info
Pregabalin 150 mg Capsule

Pregabalin 150 mg Capsule

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›150mg / 1 capsule
Manufacturer / importer
주식회사제뉴원사이언스
Appearance
A white hard capsule containing white powder
Packaging
<For domestic use> 30 capsules/bottle, 60 capsules/bottle, <For export> 30 capsules (10 capsules/PTP x 3)
Approval status
Active

MFDS item code 201109151 · Approved 2011.10.25

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive therapy for partial seizures in epilepsy, improvement of fibromyalgia
Who takes it
Adults · Children
Adult dose
This medication is taken orally in two divided doses per day, regardless of food. 1. Neuropathic Pain - Peripheral Neuropathic Pain: An initial dose of 150 mg per day may be administered, with an increase to 300 mg per day after 3 to 7 days, and subsequently, an increase to a maximum of 600 mg per day every 7 days. - Central Neuropathic Pain: The starting dose is 150 mg per day for the first week.
Child dose
There is insufficient safety and efficacy data for children under 12 years old and adolescents aged 12-17, so administration is not recommended.

Ingredients

Manufacturer
주식회사제뉴원사이언스

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive therapy for partial seizures in epilepsy, improvement of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used for the treatment of peripheral and central neuropathic pain in adults. It is also used as an adjunct in the case of partial seizures in epilepsy, whether or not there are secondary generalized symptoms. Additionally, it is applied to the treatment of fibromyalgia, helping patients relieve pain. Thus, it improves various symptoms of pain and seizures associated with neurological conditions.

How to take

Adult dose

This medication is taken orally in two divided doses per day, regardless of food. 1. Neuropathic Pain - Peripheral Neuropathic Pain: An initial dose of 150 mg per day may be administered, with an increase to 300 mg per day after 3 to 7 days, and subsequently, an increase to a maximum of 600 mg per day every 7 days. - Central Neuropathic Pain: The starting dose is 150 mg per day for the first week.

Child dose

There is insufficient safety and efficacy data for children under 12 years old and adolescents aged 12-17, so administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behavior, so mood changes and depressive symptoms should be closely monitored during treatment. This medication should not be used by individuals with allergies to its components, and patients with certain genetic lactase deficiencies should also avoid it. Diabetic patients should be cautious as weight gain after taking this medication may require adjustments to blood glucose control medications. If allergic reactions such as angioedema occur, the medication should be stopped immediately, and medical advice should be sought. Elderly patients should be particularly careful at the beginning of treatment as dizziness and drowsiness may increase the risk of falls. Transient visual disturbances or changes in vision may occur; if symptoms persist, consult a physician. Sudden discontinuation of the medication can lead to withdrawal symptoms such as insomnia, headaches, and anxiety, so the dose should be tapered gradually under medical supervision. Due to the risk of drug abuse, inform your healthcare provider about your mental health condition and history of drug use, and manage this closely. Patients with reduced kidney function may require dose adjustments. Patients with heart disease should be cautious of potential cardiovascular adverse reactions such as congestive heart failure while taking this medication. When used in combination with opioid analgesics, there may be an increased central nervous system depressant effect, so caution is advised when taken together. This medication poses a risk of respiratory depression, so adjustments may be necessary for those with respiratory or kidney diseases, as well as for elderly patients. In early pregnancy, there is a risk of congenital disabilities, so pregnant women should avoid taking this medication, and women of childbearing potential should use effective contraception. Breastfeeding women should consult with their healthcare provider about whether to stop breastfeeding or discontinue the medication, as it can be passed into breast milk. This medication may cause dizziness and drowsiness, so it is safest to avoid driving or operating dangerous machinery after taking it. Rarely, serious skin reactions may occur, so if symptoms like skin rashes or swelling occur, stop taking the medication immediately and inform your healthcare provider. In cases of overdose, symptoms such as mental confusion, drowsiness, and seizures may manifest; seek emergency treatment if suspected. This medication should be kept out of reach of children, and transferring it to another container should be avoided.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty in breathing, asthma attack, respiratory problems accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning-like headaches, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • disorientation
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • sexual sensation abnormalities
  • restlessness
  • anxiety
  • mood fluctuations
  • emotional flatness
  • emotional elevation
  • difficulty finding appropriate terms
  • hallucinations
  • abnormal dreams
  • increased sexual desire
  • panic attacks
  • impulsiveness
  • flat affect
  • ataxia
  • abnormal motor coordination
  • balance disorders
  • memory loss
  • attention impairment
  • memory impairment
  • tremors
  • speech disorders
  • sensory abnormalities
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container to protect it from air and moisture, and keep it at room temperature between 15 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a long time.

Appearance and packaging

Appearance

A white hard capsule containing white powder

Package unit

<For domestic use> 30 capsules/bottle, 60 capsules/bottle, <For export> 30 capsules (10 capsules/PTP x 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.