Diopase 160 mg Tablet (Valsartan)

Adult dose

1. Essential Hypertension - The recommended dose is 80 mg orally once a day. - If blood pressure is poorly controlled, the dose may be increased to 160 mg per day, with a maximum dose of 320 mg. - Elderly patients (75 years and older) should start with 40 mg once a day. - Patients with renal impairment, volume depletion, or liver impairment should be treated according to the recommended dosing guidelines. 2. Heart Failure - Administered 40 mg orally twice daily, with the possibility of increasing to 80 mg or 160 mg per dose. If diuretics are used concurrently, consider a reduction in the diuretic dosage. The maximum daily dose is divided into 320 mg.

Child dose

Safety and efficacy have not been established in pediatric patients and adolescents under 18 years of age.

This medication should be avoided during pregnancy, especially in the second and third trimesters, as it can cause serious harm to the fetus and newborn. If pregnancy is confirmed, treatment should be discontinued immediately. It is contraindicated in patients with an allergic reaction to this drug, severe liver disease, or significant renal dysfunction, as well as in pregnant or breastfeeding women. Elderly patients or those with hyperkalemia, impaired liver function, or heart and kidney problems should exercise caution while taking this medication, and it is advisable to start with a low dose and gradually increase it. Blood pressure may drop rapidly while taking this medication, and if dizziness or fainting occurs, consultation with healthcare professionals should be sought immediately. Patients undergoing dialysis or those on diuretics, or on strict salt restriction should be monitored carefully when starting this medication. Concomitant use with other antihypertensives, diuretics, or potassium-sparing diuretics may elevate serum potassium levels to dangerous levels, necessitating regular blood tests. Caution is advised, especially when used with non-steroidal anti-inflammatory drugs (NSAIDs), as this may reduce the blood pressure-lowering effect or worsen renal function. This medication can cause dizziness when driving or operating machinery, so caution is needed. In cases of overdose, severe hypotension, decreased consciousness, and shock may occur, requiring immediate emergency treatment. Safety in children and adolescents has not been established, so use is discouraged. This medication should be kept out of the reach of children, and care should be taken not to transfer it to other containers to avoid compromising quality or causing accidents.

Serious side effects

Hives, severe swelling (edema), angioedema (swelling of the face, lips, throat, tongue, etc.), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthmatic attack, respiratory abnormalities associated with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and very severe headache, thunderclap headache

Mild side effects

• Headache
• dizziness
• viral infections
• upper respiratory infections
• cough
• diarrhea
• fatigue
• rhinitis
• sinusitis
• back pain

This medication should be stored in a tightly sealed container to prevent air and moisture ingress, and it is important to keep it in a cool place at a temperature below 30 degrees Celsius. This helps maintain the drug's effectiveness for a long time.

Appearance

Pale yellow-brown oval film-coated tablet

Package unit

30 tablets/bottle