Coizabel Tablet 300/12.5 mg

Adult dosage

This medication is administered once daily regardless of meals. 1. For patients whose blood pressure is not sufficiently controlled with monotherapy: - For patients whose blood pressure is not adequately controlled with either Irbesartan 150 mg or Hydrochlorothiazide alone, administer 1 tablet of Irbesartan 150 mg/Hydrochlorothiazide 12.5 mg once daily. - For patients whose blood pressure is not adequately controlled with Irbesartan 300 mg or Irbesartan 150 mg/Hydrochlorothiazide 12.5 mg...

Children's dosage

The safety and efficacy of this medication have not been established in children and adolescents under 18 years of age.

This medication may cause serious harm to the fetus and newborn if administered to pregnant women. Therefore, it should be discontinued immediately upon confirmation of pregnancy. Women who are pregnant or breastfeeding, as well as patients with allergies to this medication or its components, should not take it. Patients with severely impaired renal function or anuria should also avoid this medication. Special caution is necessary for patients with hypotension, kidney disease, or liver dysfunction, and those with a history of skin cancer should regularly monitor their skin condition while on this medication. Side effects such as dizziness, fatigue, nausea, and abnormal urination may occur. Because kidney function and electrolyte levels can change as indicated by blood tests, regular monitoring is needed. Especially note the potential fluctuations in potassium levels, so caution is advised when combined with other potassium-controlling medications. This drug does not significantly affect driving or machine operation, but caution should be exercised in case of dizziness or fatigue. Additionally, there may be cases of excessive hypotension, so consultation with healthcare personnel is essential if symptoms occur. This medication can be used alongside other antihypertensives but requires caution due to interactions with lithium, certain diuretics, and non-steroidal anti-inflammatory drugs (NSAIDs). Patients scheduled for surgery should inform healthcare personnel of this medication and may need to stop taking it if necessary. Safety in children or adolescents has not been established; hence, it is not recommended. Older adults may have different sensitivities and should use it with caution. Accidental overdose may lead to hypotension, electrolyte imbalances, and dehydration symptoms, thereby requiring immediate medical attention. This medication should be stored out of the reach of children and kept in its original container.

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, high fever with severe rash, blisters, peeling skin, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthmatic attacks, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), systemic fatigue, liver abnormalities (jaundice)

Mild side effects

• Dizziness
• fatigue
• nausea
• vomiting
• abnormal urination
• increased BUN
• elevated creatine kinase
• increased creatinine
• headache
• orthostatic dizziness

This medication must be stored in a tightly sealed container to protect it from exposure to air or moisture. Additionally, it is safe to store it at room temperature, ideally between 1°C and 30°C, avoiding extremely hot or cold conditions.

Appearance

Pink, biconvex, film-coated tablets in a rectangular shape

Package unit

30 tablets/bottle