Adefovir Dipivoxil Tablet 10 mg

Adult dose

Adults: Administer 10 mg of adefovir dipivoxil orally once daily, regardless of meals. Patients with renal impairment: In patients with a creatinine clearance of less than 50 mL/min, the dosing interval should be adjusted as shown in the table below. The pharmacokinetics of adefovir have not been evaluated in patients with a creatinine clearance of less than 10 mL/min who are not receiving hemodialysis; therefore, no dosing guidelines are available for these patients.

This medication must be taken at the recommended dosage, as exceeding the dosage may be dangerous. Stopping treatment may cause sudden worsening of hepatitis, so liver function should be regularly monitored for a certain period even after discontinuation. Patients with poor liver function or cirrhosis require careful observation from the start of treatment. This drug may affect the kidneys, hence patients with poor kidney function or those taking other medications that may affect the kidneys should use it with caution. It is important to routinely conduct kidney function tests before and during treatment. Patients who are infected with HIV should check their HIV status before using this medication, and if HIV treatment is necessary, proper treatment should be received first. Caution is advised when administering this drug to pregnant women, and women of childbearing potential should use effective contraception. It is advisable to avoid breastfeeding while taking this medication. The safety and effectiveness of this drug have not been adequately established in children, adolescents, and the elderly, thus caution is required. In case of overdose, consult medical personnel immediately, and take necessary measures such as blood dialysis if needed. This medication may interact with other drugs, so it is essential to inform healthcare providers of any other medications being taken. Furthermore, this medication does not completely eliminate the risk of hepatitis B transmission, so appropriate measures to prevent infection should continue. Keep out of reach of children, and avoid transferring to other containers.

• Worsening hepatitis
• elevated ALT
• increased serum creatinine
• weakness
• headache
• fever
• abdominal pain
• nausea
• vomiting
• intestinal pneumatosis

This medication should be stored in a tightly closed container to protect it from air and moisture, preferably at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the drug and prevent deterioration.

Appearance

White to off-white round tablet

Package unit

30 tablets/bottle