Amocra Duo Tablet 500 mg (Amoxicillin - Clavulanate Potassium (7:1))

Adult dose

For adult patients with severe infections and respiratory infections, take 2 tablets orally, twice a day every 12 hours. In patients with renal impairment, the dosage may be reduced according to the degree of kidney function. In cases of severe renal failure (glomerular filtration rate less than 30 mL/min), this medication should not be administered.

This drug is a penicillin antibiotic and should not be used in patients with a history of hypersensitivity to beta-lactam drugs. Specifically, patients who have experienced severe allergic reactions such as anaphylaxis, Stevens-Johnson syndrome, or shock in the past should avoid using this medication. Additionally, patients with infectious mononucleosis or lymphocytic leukemia may have an increased risk of rash when taking this medication. Patients with impaired liver or kidney function may be adversely affected by this drug, necessitating dosage adjustment and careful monitoring. Patients with allergies, the elderly, or those with gastrointestinal diseases should also be cautious when taking this drug, paying particular attention to symptoms of vitamin K deficiency. During treatment, gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain may occur, and if severe, the patient should stop taking the medication immediately and consult a healthcare provider. Symptoms of liver dysfunction have also been reported, so it is advisable to undergo regular liver function tests during the treatment period. If signs of hypersensitivity appear, such as skin rash, hives, or difficulty breathing, the medication should be discontinued immediately, and medical advice should be followed. Prolonged use of this medication carries the risk of developing resistant bacteria and overgrowth of non-susceptible bacteria, so it is advisable to use it only for the minimum necessary duration. Pregnant women in early pregnancy or those who are breastfeeding should use this medication with caution and stop taking it if any adverse reactions appear in the infant. Special attention is needed for children and the elderly, particularly as the elderly may have an increased tendency to bleed that requires monitoring. This drug may interact with other medications, so patients are urged to inform their healthcare providers of any concurrent medications, especially when using anticoagulants or certain antibiotics. In case of overdose, gastrointestinal symptoms or neurological disturbances may occur, requiring immediate medical attention. Store in a dry place at or below 25 degrees Celsius and avoid randomly stopping or changing the dosage.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes, blisters, skin peeling, painful mucous membranes in the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by coughing and fever, liver abnormalities (jaundice), sudden and severe headaches, seizures, confusion, visual disturbances, paralysis, serious neurological symptoms,

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• nausea
• vomiting
• loss of appetite
• abdominal pain

This medication should be stored in a tightly sealed container to protect it from air and moisture, in a dry place at or below 25 degrees Celsius. Storing it this way will help maintain its effectiveness for a longer period.

Appearance

White or nearly white oblong film-coated tablets

Package unit

100 tablets (10 tablets/PTP packaging x 10)