Crescent Tablet 5 mg (Rosuvastatin Calcium)

Adult dose

The initial dose for adults is 5 mg once daily, which may be adjusted at intervals of 4 weeks or more as needed. The maintenance dose is typically 10 mg once daily, where most patients are managed at this dosage. It can be increased up to a maximum of 20 mg per day. It can be administered at any time of day, regardless of meals.

Child dose

For pediatric patients aged 10 to 17 years, the dosage may be between 5 mg and 20 mg once daily. The dosage should be adjusted according to individual treatment goals at intervals of 4 weeks or more.

This medication is contraindicated for certain patients. For example, patients allergic to any component of this medication, those with active liver disease, those with muscle disorders, and those with severe renal dysfunction should not take this medication. Pregnant or breastfeeding women, as well as women of childbearing age not using appropriate contraception, should also avoid this medication. If administered to women of childbearing age, the potential for pregnancy and risks to the fetus must be considered. Additionally, caution is required in patients vulnerable to muscle disorders, those with hypothyroidism or a family history, alcoholics, and those concomitantly taking specific medications. This medication contains lactose and should not be administered to patients with lactose intolerance or certain genetic metabolic disorders. Patients with a history of excessive alcohol consumption or liver disease should have their liver function tested before use and regularly monitor liver enzyme levels during treatment. If symptoms such as muscle pain, weakness, or cramps occur, patients should immediately inform healthcare providers and may need blood tests to check for muscle damage. Special caution is needed for the elderly, patients with reduced renal function, and patients taking certain other medications due to the heightened risk of muscle-related side effects. While this medication is not generally known to significantly affect driving ability or machine operation, caution is advised as dizziness may occur. Serious side effects such as abnormal liver function, increased risk of diabetes, and rarely severe skin reactions or interstitial lung disease may occur, necessitating immediate consultation with a physician if unusual symptoms arise. This medication may interact with other drugs, so patients should inform healthcare providers of any other medications they are taking, especially when used in combination with specific antiviral agents, antifungals, immunosuppressants, or fibrate drugs, as risks may increase. Pregnant or breastfeeding individuals should not use this medication, and women who may become pregnant should use appropriate contraceptive methods. In case of overdose, there is no specific antidote; patients should seek immediate medical attention for symptomatic treatment and evaluation.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, ocular myasthenia, rhabdomyolysis, immune-mediated necrotizing myopathy, polyneuropathy, peripheral neuropathy, thrombocytopenia, acute renal failure, oliguria, chest tightness, difficulty breathing, severe edema, severe allergic reactions, severe...

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• hematuria

This medication must be stored in a tightly sealed container to prevent air or moisture ingress. It is best stored at room temperature between 1 degree Celsius and 30 degrees Celsius, avoiding areas that are too hot or too cold.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/box (10 tablets/PTP x 3), 100 tablets/box (10 tablets/PTP x 10), 30 tablets/bottle, 100 tablets/bottle