Rosuvastatin Calcium 10 mg (Unclassified)

Adult dose

The medication can be taken at any time of the day, regardless of meals. The initial dose is 5 mg once daily, and it can be adjusted to a maintenance dose as necessary. The maintenance dose is typically 10 mg once daily, which is suitable for most patients. The dosage should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response with intervals of 4 weeks or more, and can be increased up to a maximum of 20 mg daily.

Child dose

For pediatric patients aged 10 to 17 years, a dosage of 5 mg to 20 mg is administered once daily. The dosage should be adjusted individually according to the recommended treatment goals, and intervals of 4 weeks or more should be observed.

This medication should not be used in certain patients. For example, it must not be administered to patients allergic to the components of this medication, those with severely impaired liver function, patients with muscle diseases, and those with severe renal impairment. Women who are pregnant or breastfeeding, and fertile women who are not using appropriate contraception should not take this medication. Women with potential for pregnancy should only take this medication when it is highly unlikely that they are pregnant. Patients at high risk for myopathy or rhabdomyolysis, such as those with moderate or severe renal impairment, hypothyroidism, a personal history of genetic muscle diseases, alcoholism, or those taking certain other medications should be particularly cautious, and high doses are contraindicated. This medication contains lactose, so patients with genetic metabolic disorders such as lactose intolerance or galactose intolerance should not take it. Patients who consume alcohol excessively or have a history of liver disease should undergo liver function tests before taking this medication and should monitor liver function regularly during treatment. If symptoms such as muscle pain, muscle weakness, or cramps occur, they should immediately inform a physician, and necessary blood tests should be performed to check for muscle damage. If symptoms are severe or blood test results are elevated, the medication should be discontinued. This medication can cause liver function abnormalities, increase the risk of diabetes, and rarely lead to severe skin reactions or interstitial lung disease, so any unusual symptoms should be discussed with healthcare professionals immediately. Furthermore, there are many interactions with other medications, so if other medications are being taken, healthcare professionals should be informed, especially when taken with certain antiviral drugs, immunosuppressants, antibiotics, or fibrates. In case of overdose, as there is no specific antidote, the patient should visit the hospital immediately for appropriate treatment, and liver function and muscle enzyme levels should be closely monitored. Caution is advised as dizziness may occur while driving or operating machinery. Finally, this medication may show higher blood concentrations in Asians, so dose adjustment may be necessary.

Serious side effects

Rash, angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, immune-mediated necrotizing myopathy, myopathy, severe muscle weakness, ocular myasthenia gravis, jaundice, hepatitis, severe allergic reactions, liver failure, acute renal failure, oliguria, edema, chest tightness, difficulty breathing, asthma attacks, severe skin adverse reactions

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• diarrhea
• joint pain

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree Celsius and 30 degrees Celsius at room temperature to preserve the medication's effectiveness and safety.

Appearance

Pink round film-coated tablets

Package unit

30 tablets (10 tablets/PTP × 3)