Rosuvastatin 20 mg Tablets (Rosuvastatin Calcium)

Adult dose

This medication can be taken at any time of the day, regardless of meals. The initial dose is 5 mg once daily, which can be adjusted up to 10 mg once daily as needed. The maintenance dose is adjusted every 4 weeks or more, with a maximum daily increase of up to 20 mg.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosing is 5 mg to 20 mg once daily, with adjustments made individually every 4 weeks or more.

This medication should not be used in certain patients. For instance, it should not be administered to patients who are allergic to it, have severely impaired liver function, have muscle disorders, are taking certain immunosuppressants, have severe renal impairment, or are pregnant or breastfeeding. In addition, high-dose administration is prohibited in patients at high risk for muscle disorders. This medication contains lactose and should not be given to patients with genetic issues, such as lactose intolerance. Regular liver function tests should be conducted before and during treatment, and caution is needed for those who excessively consume alcohol or have a history of liver disease. If symptoms such as muscle pain, weakness, or cramps occur, the patient should immediately inform a physician and blood tests may be needed to check for muscle damage. If severe muscle damage is suspected, the medication should be discontinued and follow the physician's instructions. This medication may increase blood sugar levels in some patients, hence those at high risk for diabetes should monitor their blood sugar. Interactions with other medications may occur during treatment; therefore, all medications being taken should be discussed with a physician or pharmacist. Women of childbearing potential should employ appropriate contraceptive methods and should not take this medication during pregnancy. In cases of overdose, there is no specific antidote, and treatment should be based on symptoms, with liver function and muscle-related tests conducted. Dizziness and other symptoms may occur, so caution is required when driving or operating machinery. This medication may have increased exposure in Asian individuals, so dosage adjustments may be necessary. If severe rash or allergic reactions occur during treatment, discontinue use immediately and consult medical personnel.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, eosinophilia and systemic symptoms drug reaction syndrome (DRESS), jaundice, hepatitis, severe allergic reactions, severe skin adverse reactions, severe muscle weakness, ocular muscle weakness, rhabdomyolysis, myopathy, immune-mediated necrotizing myopathy, thrombocytopenia, acute kidney failure, oliguria, increased serum creatinine, dyspnea, cough, interstitial lung disease,

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best to maintain the storage temperature between 1 degree Celsius and 30 degrees Celsius at room temperature.

Appearance

Pink, round film-coated tablets

Package unit

28 tablets (14 tablets/PTP*2)