Ceftriaxone Sodium Injection 1 Gram

Adult administration

Adults and children over 12 years: Administer 1～2 g (potency) of ceftriaxone once daily by intravenous or intramuscular injection. For infections caused by pathogens with moderate sensitivity or severe conditions, the dose can be increased to 4 g (potency) once a day. Elderly: Follow the same dosage instructions as adults with no need for changes. For gonorrhea treatment: A single dose of 250 mg (potency) via intramuscular injection is recommended. For pre- and post-surgical infections

Child administration

Neonates (up to 14 days old): Administer 20～50 mg (potency) per Kg body weight once daily, not exceeding 50 mg (potency). Infants and children (15 days to 12 years): 20 mg per Kg body weight

This medication should not be mixed or administered simultaneously with solutions containing calcium or other medications. Particularly, in neonates, that is, babies less than 28 days old, using this medication along with solutions containing calcium can result in dangerous precipitates, hence it should not be administered. This medication should not be used in patients with a history of allergy to certain antibiotics or local anesthetics, and it should also not be administered to premature infants and to neonates with bilirubin binding issues. When administering this medication, careful monitoring for allergic reactions, renal dysfunction, hepatic dysfunction, etc., is vital, and should any abnormal symptoms arise, medication should be stopped immediately, and appropriate treatment should be sought. This medication may cause changes in blood cell counts, gastrointestinal disturbances, skin rashes, and elevated liver enzymes, thus regular testing is necessary. Especially severe allergic reactions or shock may occur, so thorough patient history and observation prior to administration is essential, and emergency measures must be prepared. Patients receiving this medication should be cautious of dizziness while driving or operating machinery. Women who are pregnant or breastfeeding should use this medication with caution, and caution is also needed for neonates and children due to the risk of bilirubin encephalopathy. The elderly should have their dosage adjusted and their condition monitored due to increased risk of side effects due to reduced bodily functions. This medication may interact with other drugs, so consultation with a professional is required prior to co-administration. During storage, the prepared solution should be used as soon as possible and kept at appropriate temperatures.

Serious side effects

Urticaria, severe swelling (edema), cold sweat, pallor, severe allergic reactions, serious skin adverse reactions (high fever with severe rash, blisters, skin peeling, pain in oral/ocular mucosa), shortness of breath or difficulty in breathing, asthma attacks, respiratory abnormality associated with cough and fever, jaundice, generalized malaise, liver abnormalities, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, severe neurological symptoms.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• elevated liver enzymes
• headache
• dizziness
• bronchospasm
• loose stools

This medication should be stored in a sealed container to avoid exposure to air, and it is safe to store between 1 degree and 30 degrees Celsius at room temperature. Storing it this way maintains its effectiveness and prevents degradation.

Appearance

A vial containing a white to pale yellow powder

Package unit

[Domestic] 1 vial, 10 vials [Export] Method of manufacture 2: 1 vial, 10 vials Method of manufacture 3: 1 vial + 1 ampule (water for injection, 10mL)/box