Lefloxacine 250 mg (Lefloxacin Hydrate)

Adult dose

For adults, Lefloxacin is administered orally once daily at 250-750 mg. The dosing regimen for patients with normal renal function (creatinine clearance greater than 80 mL/min) is as follows: - Complicated skin and soft tissue infections: 750 mg, every 24 hours, for 10-14 days - Community-acquired pneumonia: 500 mg, every 24 hours, for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10

This medication can cause serious tendon disorders such as tendonitis and tendon rupture. If such symptoms appear, the use of this medication should be stopped immediately. Peripheral neuropathy and central nervous system abnormal symptoms may also occur, so caution is required. It should not be given to patients with myasthenia gravis as it may worsen their symptoms. This medication is used for the treatment of certain bacterial infections, but should only be used when there are no other treatment options. Co-administration with corticosteroids increases the risk of tendon rupture, so concomitant use should be avoided. Due to the risk of seizures or convulsions, it should be used cautiously in patients with epilepsy or CNS disorders. Serious allergic reactions, such as hypersensitivity or anaphylaxis, may occur, and the medication should be stopped immediately if symptoms arise. To prevent photosensitivity reactions, avoid exposure to strong sunlight or artificial UV light. Dizziness, drowsiness, and other symptoms may occur, so caution is needed when driving or operating machinery. Patients with impaired kidney or liver function require dosage adjustment and caution. This medication may affect blood glucose control, so diabetic patients should closely monitor their glucose levels. It should not be administered to pregnant or breastfeeding women or growing adolescents. In case of overdose, central nervous system symptoms and cardiac rhythm disturbances may occur, requiring immediate medical treatment. If neurological symptoms such as pain, tingling, or numbness occur during the course of this medication, use should be stopped immediately and a doctor consulted.

Serious side effects

Tendonitis and tendon rupture, peripheral neuropathy, central nervous system effects (seizures, convulsive reactions, psychotic reactions, confusion, loss of consciousness, visual disturbances, paralysis, etc.), exacerbation of myasthenia gravis, severe allergic reactions (hives, severe swelling, chest tightness, breathing difficulties, cold sweat, pallor), severe skin adverse reactions (severe rash with fever, blistering, peeling of skin, pain of oral/eye mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis

Mild side effects

Nausea, diarrhea, vaginitis, insomnia, abdominal pain, bloating, itching, dizziness, rash, indigestion, stomatitis, glossitis, dry mouth, constipation, headache, neurosis, erythematous rash, decreased appetite, drowsiness, agitation, thirst, tremors, allergic reactions, taste disturbance, vomiting, fungal infections, genital itching, genital candidiasis, renal function changes (increased serum creatinine, BUN), elevated liver enzymes (AST/ALT), ALP, γ

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is best to store it at room temperature between 1 and 30 degrees Celsius.

Appearance

Pink to dark pink rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle