TamiLin Sustained-release Tablet 8mg (Galantamine Bromide)

Adult dose

(Adults) Administer once daily in the morning. It is best taken immediately after breakfast. Swallow this medicine whole with an adequate amount of water; do not chew or crush it. Ensure adequate fluid intake while taking this medicine. Initial dose: A dose of 8mg once daily is recommended for the first 4 weeks. Maintenance dose: - After the initial dose, administer 16mg once daily for at least 4 weeks. - Thereafter, the dose may be increased up to a maximum of 24mg once daily based on assessment of clinical benefit and tolerability. - If 24mg once daily is poorly tolerated or does not improve response, consider reducing the dose to 16mg once daily. - This medicine may be continued as long as it provides benefit to the patient. Assess its clinical benefit regularly and consider discontinuing treatment if there is no therapeutic effect. - No rebound phenomenon occurs after discontinuation of treatment (e.g., in preparation for surgery). (Patients with renal or hepatic impairment) Galantamine concentrations in the blood may increase in patients with moderate to severe renal or hepatic impairment. For patients with moderate hepatic impairment, based on pharmacokinetic modeling, administer 8mg every other day for at least 1 week; morning administration is preferable. Thereafter, administer 8mg once daily for at least 4 weeks. Do not exceed 16mg per day. This medicine is contraindicated in patients with severe hepatic impairment (Child-Pugh score >9). No dosage adjustment is necessary in patients with mild hepatic impairment. No dosage adjustment is necessary in patients with a creatinine clearance of 9mL/min or higher. This medicine is contraindicated in patients with severe renal impairment (creatinine clearance < 9mL/min). (Concomitant use) Consider reducing the dose of this medicine in patients receiving CYP 2D6 or CYP 3A4 inhibitors (e.g., ketoconazole).

Child dose

Use in children is not recommended.

This medication is used to improve symptoms in patients with Alzheimer's type dementia. This medication should not be administered to individuals with an allergy to the ingredients or severe liver or kidney function impairment. Additionally, as this medication contains lactose, individuals with lactose intolerance or specific genetic metabolic disorders should not take it. During use, side effects such as nausea, vomiting, diarrhea, dizziness, headache, and bradycardia (slow heart rate) may occur, and if such symptoms appear, a consultation with healthcare professionals is necessary. In particular, if severe rash or allergic reactions occur, the medication should be stopped immediately and consultation with a doctor is recommended. It is also important to regularly check for weight changes during treatment. Patients taking medications that affect heart disease or heart rate should use this medication with caution, as it may lead to a slower heart rate or arrhythmias. Caution is also required for patients with a history of peptic ulcer illness or those recovering from gastrointestinal surgery. Patients with asthma or lung diseases should also be cautious as symptoms may worsen during use of this medication. Additionally, this medication is not recommended for patients recovering from surgery for bladder issues. This medication should not be used in conjunction with other cholinergic medications, and interactions may occur with certain antidepressants and antifungals, so patients must inform healthcare professionals of any concurrent medications. During pregnancy, administration should be done carefully considering the risks and benefits to the fetus, and breastfeeding women are advised not to take it. This medication may cause drowsiness or dizziness; caution is advised when driving or operating machinery. In cases of overdose, severe vomiting, bradycardia, and seizures may occur; immediate medical attention should be sought, and detoxification treatment may be necessary. Finally, it is safe to keep this medication out of the reach of children and not to transfer it to other containers.

Loss of appetite, depression, dizziness, headache, tremors, fainting, somnolence, drowsiness, bradycardia, nausea, vomiting, diarrhea, abdominal pain, upper abdominal pain, dyspepsia, abdominal discomfort, muscle cramps, fatigue, asthenia, lethargy, investigation, weight loss, falls, lacerations, dehydration, taste disturbance, hypersomnia, sensory disturbances, blurred vision, I degree atrioventricular block, palpitations, sinus bradycardia, ventricular premature contractions, flushing, hypotension, nausea, sweating, muscle weakness, hypersensitivity, hallucinations, visual hallucinations, auditory hallucinations, convulsions, tinnitus, complete atrioventricular block, hypertension, hepatitis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, erythema multiforme, increased liver enzymes, rash, itching, extrapyramidal syndrome, Parkinson's syndrome, worsening of Parkinson's syndrome, hand paralysis, bradykinesia, Pisa syndrome, delirium, sweating, edema, constipation, thirst, gastritis, belching, jaundice, elevated γ-GT, elevated ALT/AST, exacerbation of chronic kidney failure, urinary incontinence, vertigo, poor appetite, headache, Torsades de Pointes, QT prolongation, ventricular tachycardia, brief loss of consciousness, gastrointestinal cramps, drooling, tearing, defecation, urination, exhaustion

This medication should be stored in a tightly sealed container to protect it from air and moisture. It should be kept at room temperature between 1 degree and 30 degrees Celsius for maximum safety.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle