Midaun Capsule 120mg (Orlistat)

Adult dose

The recommended dose of this medicine is 120 mg of orlistat orally three times daily, taken with a fat-containing meal or within 1 hour after a meal. Patients should continue to follow a nutritionally balanced, mildly hypocaloric diet in which approximately 30 % of calories are from fat. Daily intake of fat, carbohydrates, and protein should be distributed evenly across three meals. This medicine may be omitted if a meal is skipped or contains no fat. As this medicine may reduce the absorption of some fat-soluble vitamins and beta-carotene, patients are advised to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition. The vitamin supplement should be taken at least 2 hours before this medicine or at least 2 hours after it, such as at bedtime. Taking more than 120 mg of this medicine three times daily does not increase its effectiveness. Measurements of fecal fat indicate that the effect of this medicine appears approximately 24 ∼ 48 hours after taking it. After treatment is discontinued, fecal fat content generally returns to pretreatment levels within 48 ∼ 72 hours. The efficacy and safety of this medicine have not been evaluated for periods exceeding 4 years. Studies have not been conducted in patients with hepatic and/or renal impairment, children under 12 years of age, or elderly patients.

This medication should not be used in patients with chronic malabsorption syndrome or biliary obstruction. Also, patients with known allergies to this medication or its ingredients, pregnant or potentially pregnant women, and breastfeeding women should not take this medication. Liver damage has been reported rarely, and a doctor should be consulted immediately if there are signs of liver function abnormalities, and a liver function test should be performed. Patients with hyperoxaluria or calcium oxalate nephrolithiasis should use this medication with caution. Taking this medication may commonly cause gastrointestinal symptoms, such as fat in stools, abdominal distension, flatulence, constipation, or diarrhea. These symptoms are usually mild and transient, typically starting within 3 months and resolving within 1 to 4 weeks. However, some patients may experience persistence for more than 6 months. Serious side effects such as hepatitis, liver failure, allergic reactions, pancreatitis, and seizures have been reported, thus symptoms should be reported to a doctor immediately. Taking this medication with a high-fat meal may increase gastrointestinal side effects; therefore, it is important to distribute fat intake evenly over three meals. Additionally, this medication may reduce the absorption of fat-soluble vitamins and beta-carotene, so it is recommended to take vitamin supplements at least 2 hours apart. Women who are pregnant or nursing should not take this medication, and safety and efficacy have not been established for children under 12 years of age. This medication may interact with other medications, especially cyclosporine, oral anticoagulants, and antiepileptics, so it is essential to follow the doctor's instructions when taking them together. In case of overdose, 24-hour observation is required, and storage recommendations include keeping it out of reach of children, protected from light and moisture.

• fatty stools
• abdominal bloating and flatulence
• increased frequency of stools
• fatty / fatty stools
• increased bowel movements
• fecal incontinence
• abdominal pain / discomfort
• nausea
• infectious diarrhea
• rectal pain / discomfort

This medication is sensitive to air, light, and moisture, so it should be stored in a tightly closed container. Additionally, it should be kept in a cool place at or below 25 degrees Celsius to maintain its efficacy.

Appearance

For domestic use: Hard capsule with upper and lower teal color containing white or whitish powder or granule. For export: Hard capsule with upper and lower teal color containing white or whitish powder.

Package unit

For domestic use: 90 capsules (10 capsules/PTPX9), 300 capsules/bottle, 30 capsules/bottle For export: 84 capsules (21 capsules/PTP X4), 21 capsules/PTP