Candemor Plus Tablets 16/12.5 mg

Adult dose

The recommended dose is 1 tablet once a day, regardless of meals. Adults should switch to this drug after adjusting the dose of candesartan cilexetil. Antihypertensive effects typically occur within 4 weeks of administration. No separate dose adjustment is needed for the elderly. Patients with reduced effective blood volume and renal impairment should have the initial dose of candesartan cilexetil adjusted; it should not be administered to patients with severe renal impairment.

This medication may increase the risk of severe harm or death to the fetus and newborn during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Individuals allergic to this drug's components or sulfonamide-class drugs, pregnant women or those planning to become pregnant, and patients with severe kidney or liver dysfunction should not take this medication. Patients with decreased blood volume or electrolyte imbalances, liver disease patients, individuals with heart valve problems, patients with hyperkalemia, the elderly, and patients with certain diseases should use this drug cautiously. This medication lowers blood pressure, so symptoms of sudden hypotension or dizziness may occur, and electrolyte imbalances may arise due to its diuretic effect, thus regular blood tests and following the physician's guidance are necessary. Due to the hydrochlorothiazide component, the skin may become sensitive to sunlight, necessitating attention to UV protection and skin care, as there is an increased risk of non-melanoma skin cancer, making it essential to periodically check skin condition. During the course of this medication, interactions may occur with other blood pressure medications, diuretics, potassium supplements, specific antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), so it is critical to inform the doctor or pharmacist of any currently taken medications. Breastfeeding women should consult a doctor or discontinue breastfeeding as this medication may pass into breast milk, and its safety and efficacy in children or adolescents under 18 years are not established. In case of overdose, symptoms such as hypotension, dizziness, and electrolyte imbalance may occur, requiring immediate visit to a medical institution, and it should be stored out of reach of children in its original container for safety. Caution is advised when driving or operating machinery as dizziness or fatigue may occur.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reaction, angioedema, intestinal vascular edema, anaphylactic reaction, severe skin adverse reactions, angioedema, rash, hives, liver abnormalities (jaundice), jaundice (intrahepatic cholestasis), acute respiratory distress syndrome, shortness of breath or difficulty breathing, acute angle-closure glaucoma, pulmonary edema, acute respiratory distress, severe edema accompanied by increased blood pressure.

Mild side effects

• Headache
• back pain
• dizziness
• respiratory tract infections
• symptoms similar to a cold
• sinusitis
• bronchitis
• urinary tract infections
• nausea
• bruising

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is best kept in a cool place at temperatures below 30 degrees Celsius. This will help maintain the medication's effectiveness and prevent deterioration.

Appearance

Biconvex light orange oval tablet

Package unit

30 tablets/bottle, 100 tablets/bottle