Medication info
Rectasin Tablet 250 mg (Levofloxacin Hydrate)

Rectasin Tablet 250 mg (Levofloxacin Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›256.15mg / 1 tablet
Manufacturer / importer
유니메드제약(주)
Appearance
Pink oblong film-coated tablet
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 200804225 · Notified 2008.04.17 · Insurance code 649505100

Summary

Main use
Treatment of bacterial infections such as complicated skin and soft tissue infections, community-acquired pneumonia.
Who takes it
Adults
Adult dose
Typically, for adults, levofloxacin is taken orally once daily at a dose of 250 to 750 mg. 1. Patients with normal kidney function (creatinine clearance greater than 80 mL/min) - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10 to 14 days. - Community-acquired pneumonia: 500 mg every 24 hours for 7 days. - Acute bacterial exacerbation of chronic bronchitis: 7 days. - Acute sinusitis: 10 to 14 days. - Chronic.

Ingredients

Manufacturer
유니메드제약(주)

Efficacy & effects

Treatment of bacterial infections such as complicated skin and soft tissue infections, community-acquired pneumonia.

  • Complicated skin infections
  • soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary tract infections
  • uncomplicated urinary tract infections.
View approved original text

This drug is effective against a variety of bacteria and is primarily used to treat several infections such as complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, and urinary tract infections. However, as a fluoroquinolone antibiotic, it may cause significant side effects and is used only when other treatments are ineffective for acute bacterial sinusitis, acute exacerbation of chronic bronchitis, uncomplicated urinary tract infections, and complicated skin and soft tissue infections. The use of this medication is determined after careful consideration of the patient's individual condition. Therefore, this drug helps improve specific bacterial infections.

How to take

Adult dose

Typically, for adults, levofloxacin is taken orally once daily at a dose of 250 to 750 mg. 1. Patients with normal kidney function (creatinine clearance greater than 80 mL/min) - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10 to 14 days. - Community-acquired pneumonia: 500 mg every 24 hours for 7 days. - Acute bacterial exacerbation of chronic bronchitis: 7 days. - Acute sinusitis: 10 to 14 days. - Chronic.

Precautions

This drug may cause tendon-related disorders such as tendinitis and tendon rupture, so use should be discontinued immediately if pain or inflammation occurs. Peripheral neuropathy or central nervous system symptom may also appear, and if such symptoms occur, medication should be stopped and a physician consulted. Patients with myasthenia gravis may experience exacerbation of symptoms when taking this medication, so it is not recommended for use. This drug is used only for the treatment of specific bacterial infections and is administered only when there are no other treatment options. Elderly patients or those with impaired kidney function, and those taking corticosteroids are at higher risk for tendon rupture and should be used cautiously. Patients who have experienced side effects from similar medications in the past, individuals under 18 years of age, pregnant and nursing women, and those with epilepsy should not be administered this drug. Patients at risk of seizures or those with central nervous system disorders should be administered with caution and should immediately discontinue the medication if seizures occur. Exposure to strong sunlight or artificial ultraviolet lights should be avoided during use, and if skin rashes or hypersensitivity reactions occur, use should be discontinued. Dizziness, drowsiness, and visual disturbances may occur, so caution is needed while driving or operating machinery. Blood sugar levels may change when taken with antidiabetic medications, so blood levels should be checked frequently. Severe skin reactions, blood abnormalities, liver dysfunction, kidney problems, and other serious side effects may occur, so medical consultation is required immediately if abnormal symptoms appear. In case of overdose, central nervous system symptoms and cardiac abnormalities may occur, necessitating immediate treatment, and caution is required as it is not removed by hemodialysis. This drug has not been confirmed to be safe for use in children or adolescents who are still growing. Elderly patients may require dose adjustment due to prolonged drug retention in the body resulting from decreased kidney function, increasing the risk of side effects. Patients with aortic aneurysms or heart valve diseases may experience increased risks during use of this drug, so special caution is necessary.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination.

Mild side effects

  • Nausea
  • diarrhea
  • vulvovaginitis
  • insomnia
  • abdominal pain
  • bloating
  • itching
  • dizziness
  • rash
  • dyspepsia
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  • stomatitis
  • glossitis
  • dry mouth
  • constipation
  • vomiting
  • fungal infections
  • genital itching
  • headache
  • neurosis
  • erythematous rash
  • decreased appetite
  • drowsiness
  • agitation
  • thirst
  • tremor
  • allergic reactions
  • palpitations
  • QT interval prolongation
  • arrhythmia
  • increased BUN
  • elevated serum creatinine
  • increased AST/ALT
  • elevated ALP
  • γ-GTP.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and humidity, so it should be stored in a tightly closed container. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. This helps maintain the drug's efficacy and safety for a longer period.

Appearance and packaging

Appearance

Pink oblong film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.