Titonele Tablet 35 mg (Risedronate Sodium 2.5 Hydrate)

Adult dose

Risedronate sodium 35 mg orally once a week. Food can interfere with absorption, so take at least 30 minutes before breakfast or at least 2 hours before or after eating food or drinking. It should be taken upright with plenty of plain water (170 to 230 mL) and should not be chewed or sucked. Do not lie down for at least 30 minutes after taking.

Child dose

Safety and efficacy in children under 18 have not been established.

This medication can irritate the gastric and esophageal mucosa, so caution is advised for individuals with gastritis or esophageal disorders. Patients with esophageal issues or difficulty swallowing should avoid this medication. When taking it, consume with plenty of water, and do not lie down for at least 30 minutes after taking. Pregnant or breastfeeding women should not use this drug. Patients with severely impaired kidney function should also avoid this medication. If symptoms such as esophageal pain, difficulty swallowing, or heartburn occur during use, discontinue immediately and consult a doctor. It is important to supplement calcium or vitamin D if deficient. This drug may interfere with the absorption when taken with food or other medications containing calcium or magnesium, so timing should be adjusted. Rare side effects, such as osteonecrosis of the jaw or atypical fractures, may occur with long-term use; consult healthcare professionals if these symptoms arise. Pay attention to oral hygiene while taking this medication, and consult a doctor if invasive dental treatment is needed. Generally safe for the elderly, but should be monitored closely for adverse reactions. In case of overdose, blood calcium levels may drop, so seek medical care if symptoms occur. Safety and efficacy in children under 18 have not been established.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in the oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough + fever, yellowing of the skin or eyes (jaundice), significant lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Dyspepsia
• diarrhea
• abdominal pain
• nausea
• headache
• weakness
• throat pain
• chest pain
• allergic reactions
• hypertension

This medication should be stored in a tightly sealed container to prevent air and moisture. The storage temperature should be maintained at room temperature between 1 degree and 30 degrees Celsius. This helps maintain the medication's effectiveness safely for a long time.

Appearance

Pale orange rectangular film-coated tablet

Package unit

4 tablets/PTP