Sulbactam Amoxicillin Tablet 500mg (Amoxicillin-Sulbactam Coated Tablet)

Adult dose

Administer 500 - 1000 mg (based on potency) of amoxicillin-sulbactam per dose orally three times a day.

Child dose

Children over 12 years: administer 500 - 1000 mg (based on potency) of amoxicillin-sulbactam per dose orally three times a day.

This medication contains penicillin-class antibiotic ingredients and should not be used in patients who are hypersensitive to any component of this medication or to penicillin-class antibiotics. Additionally, patients with hypersensitivity to cephalosporins or those with viral infections such as infectious mononucleosis should not take this medication. Since this medication contains lactose, it should not be administered to patients with lactose intolerance or hereditary metabolic disorders. Patients with a history of gastrointestinal disease or multiple allergic reactions, patients who are prone to bronchial asthma or skin allergies should use this medication with caution. Patients with severely impaired kidney function may have high drug concentrations maintained, so dosing intervals should be adjusted and they should be closely monitored. Patients who have difficulty swallowing or those who are older, and patients in poor overall condition should also be carefully managed, due to the risk of bleeding from vitamin K deficiency. This medication can cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal pain, and in case of severe diarrhea or bloody stools, the medication should be stopped immediately and appropriate treatment should be received. Hypersensitive reactions may include skin rashes, urticaria, serum sickness-like reactions, and rarely anaphylactic shock, so any unusual symptoms should prompt immediate consultation with medical personnel. Can impact the kidneys, and if symptoms of nephritis or acute renal failure occur, the medication should be discontinued, and appropriate measures should be taken. Hematological anomalies such as anemia, thrombocytopenia, and leukopenia have been reported, thus regular blood tests are necessary. Long-term use may increase the likelihood of fungal infections, therefore if symptoms of stomatitis or candidiasis appear, the medication should be stopped. Skin eruptions, itching and in severe cases, serious skin reactions such as Stevens-Johnson syndrome can occur, necessitating careful observation. Liver dysfunction or jaundice may occur, thus regular liver function tests should be conducted. Rarely, neurological abnormalities such as seizures, headaches, and aseptic meningitis have been reported; if symptoms occur, the medication should be discontinued immediately. This medication may interact with other drugs; therefore, if there are medications being taken concurrently, it is essential to inform healthcare professionals. During pregnancy, the risk to the fetus is low, but should only be used when the therapeutic benefits outweigh the risks, and should be used cautiously while breastfeeding. In children and the elderly, dosages and intervals should be adjusted based on kidney function and overall condition, and careful observation is advised. In cases of overdose, neurological toxicity or renal failure may occur, so if suspected, immediate treatment should be sought.

Serious side effects

• Urticaria
• severe swelling (Quincke's edema)
• anaphylactic shock
• severe allergic reactions
• membranous colitis
• severe colitis with bloody stools
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• erythema multiforme
• exfoliative dermatitis

Mild side effects

Nausea, vomiting, diarrhea, loss of appetite, upper abdominal pain, rash, serum sickness-like arthralgia, myalgia, skin rash, hypersensitivity vasculitis, purpuric rash, elevated BUN and creatinine levels related to kidneys, hematological abnormalities (anemia, platelet disorders, neutropenia, etc.), microbial imbalance (stomatitis, candidiasis, etc.), itching, skin rash, hyperbilirubinemia, elevated liver enzymes, headache, fatigue, malaise, chills, vascular swelling

This medication should be stored in a tightly sealed container to protect it from air and moisture, and should be kept at room temperature between 1 to 30 degrees Celsius. Storing under these conditions helps maintain the efficacy of the medication and prevent deterioration.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle