Pharmac gabapentin capsule 100 milligrams

Adult dose

Monotherapy and adjunctive therapy for epilepsy in patients aged 13 years and older: To achieve a maintenance dose of 900 mg/day of gabapentin, titrate gradually over the first 3 days of treatment as follows. Day 1: Administer one 300 mg capsule of this medicine once daily, or one 100 mg capsule of this medicine 3 times daily (gabapentin 300 mg/day) Day 2: Administer one 300 mg capsule of this medicine twice daily, or 2 capsules of this medicine 100 mg 3 times daily (gabapentin 600 mg/day) From Day 3 onward: Administer one 300 mg capsule of this medicine 3 times daily, or 3 capsules of this medicine 100 mg 3 times daily (gabapentin 900 mg/day) Alternatively, as a starting dose, one 300 mg capsule of this medicine may be administered 3 times daily (gabapentin 900 mg/day). The dose may be increased to 1,200 mg/day of gabapentin, and the total daily dose must not exceed 2,400 mg of gabapentin. (There are insufficient data on the safety and efficacy of doses exceeding 2,400 mg/day of gabapentin.) Adults with neuropathic pain (18 years and older): To achieve a maintenance dose of 900 mg/day of gabapentin, titrate gradually over the first 3 days of treatment as follows. Day 1: Administer one 300 mg capsule of this medicine once daily, or one 100 mg capsule of this medicine 3 times daily (gabapentin 300 mg/day) Day 2: Administer one 300 mg capsule of this medicine twice daily, or 2 capsules of this medicine 100 mg 3 times daily (gabapentin 600 mg/day) From Day 3 onward: Administer one 300 mg capsule of this medicine 3 times daily, or 3 capsules of this medicine 100 mg 3 times daily (gabapentin 900 mg/day) Alternatively, as a starting dose, one 300 mg capsule of this medicine may be administered 3 times daily (gabapentin 900 mg/day). If necessary, the dose may be increased to 1,800 mg/day of gabapentin within one week, and the total daily dose must not exceed 3,600 mg of gabapentin. When taking this medicine, the total daily dose should be divided into 3 doses. Debilitated patients: In debilitated patients with low body weight or patients after transplant surgery, the gabapentin dose should be increased in increments of 100 mg. Elderly patients: Dosage adjustment may be necessary due to age-related decline in renal function (see table). Patients with renal impairment (creatinine clearance of 80 mL/min or less) or patients undergoing hemodialysis: Dosage adjustment is required based on the following table. Renal function, creatinine clearance (mL/min) ≥80: Total daily dosea (mg/day) 900∼2,400 Renal function, creatinine clearance (mL/min) 50∼79: Total daily dosea (mg/day) 600∼1,800 Renal function, creatinine clearance (mL/min) 30∼49: Total daily dosea (mg/day) 300∼900 Renal function, creatinine clearance (mL/min) 15∼29: Total daily dosea (mg/day) 150b∼600 Renal function, creatinine clearance (mL/min) <15: Total daily dosea (mg/day) 150b∼300 a: The total daily dose should be divided into 3 doses. b: Administer 3 × 100 mg every 2 days. In patients with creatinine clearance below 15 mL/min, the dose should be reduced in proportion to creatinine clearance. Dosage in patients on hemodialysis Initial dose: 300∼400 mg of gabapentin is recommended. Maintenance dose: Administer 200∼300 mg of gabapentin after 4 hours of hemodialysis, and do not administer this medicine on days when hemodialysis is not performed. Swallow this medicine whole with sufficient fluid. It may be taken with or without food. When administered 3 times daily, take care that the interval between doses does not exceed 12 hours to prevent recurrence of seizures. If a dose of this medicine is missed (if more than 12 hours have elapsed since the last dose), the physician should decide whether an additional dose should be taken to make up for it. When used concomitantly with antacids containing magnesium or aluminum, administer this medicine at least 2 hours after the antacid. The duration of treatment with this medicine should depend on clinical need. Treatment of epilepsy generally requires long-term administration. If treatment with this medicine is to be discontinued, or if it is to be administered concomitantly with another antiepileptic drug, the change should be made gradually over at least 1 week. The safety and efficacy of treatment for neuropathic pain for more than 5 months have not been evaluated. To reduce the main adverse effects, such as somnolence, dizziness, fatigue, and ataxia, the first dose on the first day of treatment should be taken at bedtime.

Child dose

Adjunctive therapy for children aged 3 years to 12 years: To achieve a maintenance dose of 30 mg/day of gabapentin per kg of body weight, titrate over the first 3 days of treatment as follows. Day 1: Administer 10 mg/kg of body weight of gabapentin Day 2: Administer 20 mg/kg of body weight of gabapentin From day 3: Administer 30 mg/kg of body weight of gabapentin The dose may be increased, if necessary, to a maximum of 40 mg per kg of body weight per day. Divide the total daily dose of this medicine into 3 doses.

This drug is used as an antiepileptic agent to control seizures. There is an increased risk of mental health issues such as suicidal thoughts, suicidal behavior, and depression during treatment, so if these symptoms arise, consult a doctor immediately. Abruptly stopping this medication can lead to worsening seizures or persistent seizure states, so it must be discontinued gradually under a doctor's instruction. Animal studies reported a potential for certain cancers, but risks in humans are unclear. There have been reports of sudden and unexpected death during treatment, which may relate to the risks of epilepsy itself. Serious side effects such as pancreatitis may occur during treatment, so if persistent upper abdominal pain, nausea, or vomiting occurs, discontinue use immediately and inform a physician. Particularly in children aged 3 to 12 years, neuropsychiatric adverse reactions such as emotional instability, aggression, decreased concentration, and hyperactivity may occur, so caution is required. This medication can increase the risk of severe sedation, respiratory depression, coma, or death when taken concurrently with central nervous system depressants like narcotics, so strict medical supervision is required when used together. Allergic reactions or severe skin reactions may occur; if symptoms such as rash, fever, or lymph node swelling arise, discontinue use immediately. There may be risks to the fetus during pregnancy, so consult a doctor if pregnant or planning to become pregnant. Nursing mothers should also exercise caution, and decisions should be made in consultation with a healthcare provider if necessary. Drowsiness or dizziness may occur; caution is advised when driving or operating machinery, and the prescribed dosage and schedule should be strictly adhered to. Patients with decreased kidney function or the elderly may require dosage adjustments, so follow a doctor's instructions. There may be weight gain during treatment, so regular weight monitoring and, if necessary, management of diet and exercise are recommended. Overdosage may lead to coma or other serious conditions; take care not to exceed the recommended dosage and seek immediate medical attention in emergency situations.

Suicidal thoughts, suicidal behavior, depression, abnormal changes in mood and behavior, hemorrhagic pancreatitis, emotional instability, hostility, thought disorder, hyperactivity, weakness, lethargy, facial swelling, hypertension, constipation, abnormal teeth, diarrhea, dyspepsia, increased appetite, thirst, nausea, vomiting, leukopenia, peripheral edema, weight gain, fractures, myalgia, amnesia, ataxia, confusion, impaired coordination, dizziness, dysarthria, insomnia, neuroexcitability, nystagmus, drowsiness, thought disorder, tremor, single contraction, cough, pharyngitis, rhinitis, abrasion, acne, pruritus, rash, amblyopia, diplopia, erectile dysfunction, asthenia, fatigue, facial swelling, allergy, generalized edema, weight loss, chills, feeling of unfamiliarity, lethargy, alcohol intolerance, hangover effect, hypotension, angina, peripheral vascular disorder, palpitations, tachycardia, migraine, noise, atrial fibrillation, heart failure, thrombophlebitis, myocardial infarction, cerebrovascular accident, pulmonary thrombosis, ventricular extrasystole, bradycardia, immature atrial contraction, pericardial friction, heart block, pulmonary embolism, hyperlipidemia, hypercholesterolemia, pericardial effusion, pericarditis, anorexia, abdominal distension, gingivitis, glossitis, gum bleeding, thirst, stomatitis, increased salivation, gastroenteritis, hemorrhoid, bloody stools, fecal incontinence, hepatomegaly, dysphagia, belching, pancreatitis, gastric ulcer, colitis, oral vesicles, dental discoloration, angular cheilitis, salivary gland hypertrophy, lip bleeding, esophagitis, hiatal hernia, hematemesis, proctitis, irritable bowel syndrome, rectal bleeding, esophageal spasm, hyperthyroidism, hypothyroidism, thyroid enlargement, low estrogen, ovarian failure, epididymitis, testicular swelling, Cushing's syndrome, bruising from trauma, anemia, lymphadenopathy, thrombocytopenia, leukocytosis, lymphocytosis, Hodgkin's lymphoma, increased bleeding time, arthralgia, tendinitis, arthritis, joint stiffness, joint swelling, benign Romberg test, costochondritis, osteoporosis, tenosynovitis, contracture, dizziness, hyperactivity, sensory disturbances, decreased or absent reflexes, increased reflexes, anxiety, hostility, CNS tumors, syncope, dream disorders, aphasia, sensory loss, intracranial hemorrhage, hypotonia, paresthesia, incomplete paralysis, myotonia, hemiplegia, facial paralysis, confusion, cerebellar dysfunction, benign Babinski sign, loss of proprioception, subdural hematoma, apathy, hallucinations, decreased or lost libido, restlessness, schizoid personality, depersonalization, dysphoria, hyperesthesia, hallucinatory states, suicidal impulses, mental disorders, chorea like athetosis, peri-oral movement disorders, brain disorders, nerve paralysis, personality disorders, increased libido, organic suppression, apraxia, fine motor control disorders, meningocele, focal myoclonus, hypersensitivity, decreased motor function, mania, neurosis, hysteria, antisocial responses, suicidal behavior, pneumonia, epistaxis, dyspnea, apnea, mucositis, aspiration pneumonia, hyperventilation, hiccups, laryngitis, nasal congestion, nasal obstruction, bronchospasm, hypoventilation, pulmonary edema, hair loss, eczema, dry skin, increased sweating, urticaria, hirsutism, seborrhea, cysts, herpes simplex, herpes zoster, skin discoloration, skin nodules, photosensitivity, leg ulcers, scalp seborrhea, psoriasis, epidermal detachment, maceration, skin granulomas, necrosis of the skin, localized swelling, hematuria, urination disorders, frequent urination, cystitis, urinary retention, urinary incontinence, vaginal bleeding, amenorrhea, menstrual disorders, menorrhagia, breast cancer, anovulation, ejaculation disorders, kidney pain, leukorrhea, genital pruritus, kidney stones, acute renal failure, anuria, diabetes, nephritis, nocturnal enuresis, pyuria, urgency in urination, dyspareunia, mastalgia, testicular pain, visual disturbances, cataracts, conjunctivitis, dry eye, ocular pain, photophobia, bilateral or unilateral ptosis, ocular hemorrhage, chalazion, hearing loss, ear pain, tinnitus, otitis interna, ear inflammation, taste loss, taste disturbances, blepharospasm, ocular fullness, eye pruritus, accommodation disorders, tympanic membrane perforation, noise sensitivity, abnormal fixation of the eyes, overflow tearing, retinopathy, glaucoma, iritis, corneal disorders, lacrimal dysfunction, retinal degeneration, blindness, retinal detachment, miosis, chorioretinitis, strabismus, Eustachian tube dysfunction, otitis interna, otitis externa, olfactory disturbances, urinary tract infections, urination disorders, erectile dysfunction, urinary incontinence, vaginismus, mastalgia, menstrual disorders, polyuria, urinary retention, cystitis, ejaculation disorders, penile enlargement, gynecomastia, nocturnal enuresis, pyelonephritis, scrotal swelling, frequent urination, urgency, urinary abnormalities, tongue paralysis, increased serum creatine phosphokinase, rhabdomyolysis, acute renal failure, urticaria, allergic reactions, anaphylaxis, angioedema, hyperglycemia, hypoglycemia, breast enlargement, chest pain, toxic epidermal necrolysis, eosinophilia, drug rash accompanied by systemic symptoms, elevated liver function tests, erythema multiforme, falls, generalized edema, gynecomastia, hallucinations, hepatitis, hypersensitivity with systemic reactions, hyponatremia, jaundice, loss of consciousness, chorea like athetosis, movement disorders, myotonia, muscular dystrophy, palpitations, pancreatitis, sexual dysfunction, mucocutaneous syndrome, thrombocytopenia, tinnitus, urinary incontinence, anxiety, insomnia, nausea, pain, sweating, tremors, headache, abnormal sensation, lethargy

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Additionally, the medication should be kept at a cool room temperature, ideally between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for an extended period.

Appearance

A hard capsule that is white or off-white containing powder.

Package unit

30 capsules/bottle, 300 capsules/bottle