Clarithromycin Tablet 500mg (Clarithromycin)

Adult dosage

○ Adults : The usual dose is 250mg (potency) of clarithromycin per dose, administered twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer this medicine to such patients for more than 14 days. ○ Mycobacterial infections : Administer 500mg (potency) of this medicine per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer : For 14 days, administer 500mg (potency) of this medicine three times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: same as adults For children under 12 years, use clarithromycin dry syrup.

This medication should not be used by individuals who are allergic to certain components or have had hypersensitivity reactions to macrolide antibiotics. Additionally, patients with arrhythmias or severe liver or kidney dysfunction should not take this medication. It is also safer for pregnant or breastfeeding women to avoid this medication. Since this medication may cause serious side effects such as arrhythmias when used with certain other medications, it is crucial to inform your healthcare provider of any medications you are currently taking. Patients with weak liver or kidney function should use this medication cautiously, and dosage adjustment may be necessary. During the use of this medication, allergic reactions, gastrointestinal disturbances, skin rashes, neurological symptoms may occur, and if any unusual symptoms arise, immediate consultation with a healthcare professional is necessary. Additionally, this medication may affect intestinal bacterial balance, so if symptoms of diarrhea or colitis appear, it should be discontinued, and appropriate treatment should be sought. Long-term or repeated use may lead to the development of resistant bacteria, so it should only be taken for the minimum duration as directed by a physician. This medication interacts with many other drugs, so if you are taking other medications, you must inform your healthcare provider, and if necessary, blood tests or electrocardiograms may be conducted. Special caution is needed for certain patient groups such as pregnant women, breastfeeding mothers, the elderly, and children, so consultation with a specialist is essential before use. In case of overdose, gastrointestinal disturbances or neurological symptoms may occur, requiring immediate medical attention, and blood dialysis or peritoneal dialysis will be ineffective.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal fullness, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, epigastric pain, cramping type epigastric pain, thirst, transient teeth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, fecal discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, orientation disturbance, hallucination, psychosis, depersonalization, convulsions, tremors, paresthesia, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash associated with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, myalgia, weakness, elevated CPK, elevated serum myoglobin, elevated urine myoglobin, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disorder, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, auditory impairment, hypoglycemia, purpuric rash, acute generalized pustular eruption, muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea, venous inflammation at injection site, pain at injection site, inflammation at injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine discoloration, soft tissue infection, candidiasis, gastroenteritis, infection, vaginitis, shingles, superficial soft tissue infection, erythema nodosum, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactic reaction, hypersensitivity, anaphylactic response, angioedema, anorexia, decreased appetite, hypoglycemia, insomnia, anxiety, nervousness, noise sensitivity, psychotic disorder, confusional state, depersonalization, depression, orientation disturbance, hallucination, abnormal dreams, mania, taste disturbance, headache, loss of consciousness, movement disorder, non-vestibular dizziness, drowsiness, tremor, convulsions, taste loss, abnormal sense of smell, loss of smell, vestibular dizziness, hearing impairment, hearing loss, cardiac arrest, atrial fibrillation, prolonged QT interval on ECG, ectopic beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, diarrhea, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, tongue discoloration, teeth discoloration, abnormal liver function tests, cholestasis, hepatitis, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated gamma-glutamyl transferase, liver failure, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura

This medication should be stored in a sealed container, protected from air and moisture. It should also be kept in a dark place to prevent exposure to light, and it is important to maintain a dry environment. The storage temperature should be maintained between 15 to 30 degrees Celsius.

Appearance

Yellow oblong film-coated tablet

Package unit

In-house packaging unit