Prosaid Tablet (Bicalutamide)

Adult dose

1. Adults and elderly men receiving this medicine in combination with a luteinizing hormone-releasing hormone (LHRH) analog or surgical castration : Administer 50 mg of bicalutamide orally once daily. Start taking this medicine at least 3 days before administration of the luteinizing hormone-releasing hormone (LHRH) analog or at the same time as surgical castration. 2. Monotherapy in patients with locally advanced, nonmetastatic prostate cancer at high risk of disease progression, or adjuvant therapy to radical prostatectomy or radiation therapy : Adult and elderly men: Administer 150 mg of bicalutamide orally once daily. Continue this 150 mg regimen for at least 2 years or until the disease progresses.

This drug should not be used by women or children under 18 years of age. Patients with allergic reactions to this drug or its components should avoid administration. This drug should not be used in conjunction with specific medications such as terfenadine, astemizole, or cisapride. It is safe not to administer this drug to patients with a history of liver damage or severely impaired liver function. This drug contains lactose, so caution is needed for patients with lactose intolerance or related genetic disorders. In patients with impaired liver function, this drug may be excreted slowly, increasing the risk of drug accumulation, thus careful use is recommended. While taking this drug, side effects such as anemia, dizziness, flushing, digestive disorders, rash, hematuria, gynecomastia, weakness may occur. Liver function abnormalities or hepatotoxic symptoms may rarely occur, so regular liver function tests are necessary. Since this drug is primarily metabolized in the liver, caution is required when taken with other medications affecting the liver. There may be confusion or drowsiness when operating vehicles or machinery, so caution is advised. Changes in blood sugar control may occur during treatment with this drug, therefore, diabetic patients should manage their blood sugar levels well. Patients with heart disease or who are at risk of QT interval prolongation should consult healthcare professionals before taking this drug. Pregnant or breastfeeding women should not take this drug. There is no specific antidote in case of overdose; therefore, appropriate treatment according to the symptoms is needed, and dialysis may not be effective. This drug should be kept out of the reach of children, stored in its original container to maintain quality.

• Anemia
• dizziness
• facial flushing
• abdominal pain
• constipation
• nausea
• diarrhea
• rash
• hematuria
• gynecomastia

This medication should be stored in an airtight container and kept at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness and prevent degradation.

Appearance

White round film-coated tablet

Package unit

28 tablets (14 tablets/PTP*2)