Bynex Carvedilol Tablet 12.5 mg

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. Essential hypertension Adults: For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. The usual dosage is 25 mg orally once daily for 2 weeks. If an increase is needed, increase to 25 mg per dose twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. Older adults: In some older adults, 12.5 mg once daily may be sufficient to produce an adequate effect. However, the dose may be increased if the effect is insufficient after 2 weeks of administration. Chronic stable angina For the first 2 days, administer 12.5 mg of this medicine per dose twice daily orally, then administer 25 mg per dose twice daily orally. The usual dosage is 25 mg per dose twice daily for 2 weeks. If an increase is needed (excluding older adults), the dose may be increased to 50 mg per dose twice daily. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard treatment regimen (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. The usual initial dosage is 3.125 mg of this medicine per dose twice daily orally for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg per dose twice daily for 2 weeks, then to 12.5 mg per dose twice daily for 2 weeks, and then to 25 mg per dose twice daily. After taking each dose for at least 2 weeks, gradually increase the dose to the highest dose the patient can tolerate. The minimum effective dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less, and 50 mg per dose twice daily for patients weighing more than 85 kg. To control the rate of absorption, it is recommended that the medicine be taken with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be administered to certain patients. For example, individuals with a history of allergy to this medication or its components, patients in cardiac shock, those with severe cardiac conduction problems, patients with cor pulmonale, diabetic ketoacidosis patients, those with severely impaired heart function, asthmatic or chronic obstructive pulmonary disease patients, secondary hypertension patients, Prinzmetal angina patients, acute pulmonary embolism patients, certain hormone tumor patients, those taking MAO inhibitors, patients with severe hypotension, patients with severe liver dysfunction, women who are pregnant or breastfeeding, patients with peripheral circulation disorders, patients with laryngeal edema, patients with complications after a heart attack, patients with fluid overload, allergic rhinitis patients, and patients with genetic problems such as lactose intolerance should not use this medication. Caution should also be exercised in patients with diabetes, those with a history of severe allergies or undergoing sensitive treatment, patients with skin disorders due to beta-blockers, patients with hypotension or renal insufficiency, unstable angina patients, chronic congestive heart failure patients, patients with severe renal impairment, patients with mild bradycardia, the elderly, patients with acute heart diseases, patients taking specific antihypertensive medications, patients with low salt or fluid levels, patients on certain heart medications, fasting patients, patients with hyperthyroidism, contact lens wearers, minors under 18 years of age, and patients who are unstable after acute myocardial infarction, as caution is warranted. When taking this medication, dizziness, headaches, and fatigue may occur, and rarely, central nervous system symptoms such as hallucinations, confusion, depression, and sleep disturbances may occur. Cardiac-related side effects include excessively slowed heart rate, cardiac shock, and worsening heart failure, necessitating regular cardiac evaluations. There may also be rapid drops in blood pressure or loss of consciousness. Additionally, deterioration of renal function, increased respiratory resistance, gastrointestinal symptoms, skin rashes, changes in blood cell counts, endocrine issues, liver dysfunction, and other pains or allergic reactions may occur, so caution is advised. Regular monitoring of cardiac function, blood pressure, electrocardiograms, and liver and kidney function is necessary for patients who take this medication over the long term, and abrupt cessation of the medication may worsen symptoms; therefore, it must be gradually tapered under a physician's guidance. The elderly, hypotensive patients, diabetic patients, and those with poor renal function should exercise even more caution. Also, care must be taken as dizziness or drowsiness may occur when driving or operating hazardous machinery. This medication can interact with various drugs, so if other medications are being taken, it is crucial to inform your doctor or pharmacist. Caution is particularly necessary when taken with antihypertensives, antidepressants, hypoglycemics, calcium channel blockers, antiarrhythmics, anesthetics, alcohol, etc., as there may be an increased risk of side effects or changes in effectiveness. Pregnant or breastfeeding women should not take this medication, as it may cause severe side effects in the fetus or newborn. The safety of this medication in minors and adolescents under 18 has not been established, and its use is not recommended. The elderly may experience increased blood concentrations of this medication due to impaired liver function, and there is a risk of excessive blood pressure reduction leading to strokes; thus, starting with a low dose and administering it cautiously is advised. In the event of an overdose, severe hypotension, decreased heart rate, diminished cardiac function, shock, respiratory distress, and altered consciousness may occur; immediate medical attention is required, and detoxification and supportive treatment may be necessary for a prolonged period. This medication should be stored in a light-resistant container as it can discolor due to light exposure, and it should be kept out of reach of children. Transferring to another container is not advisable for maintaining quality.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication is sensitive to light, so it should be stored in a container that does not allow light penetration. It's best to maintain a storage temperature between 1°C and 30°C to ensure the prolonged effectiveness and safety of the medication.

Appearance

Brownish-red round tablet

Package unit

100 tablets (10 tablets/PTP × 10)